Demerol and Cyproheptadine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demerol (meperidine hydrochloride) and Cyproheptadine hydrochloride (cyproheptadine hydrochloride). Common drug interactions include abscess jaw among females.

The phase IV clinical study analyzes what interactions people have when they take Demerol and Cyproheptadine hydrochloride. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

What is Cyproheptadine hydrochloride?

Cyproheptadine hydrochloride has active ingredients of cyproheptadine hydrochloride. It is often used in migraine. eHealthMe is studying from 1,075 Cyproheptadine hydrochloride users. Check the latest studies of Cyproheptadine hydrochloride.



On Jul, 19, 2026

15 people who take Demerol and Cyproheptadine hydrochloride together, and have interactions are studied.

Demerol and Cyproheptadine hydrochloride drug interactions.

What are the common drug interactions of Demerol and Cyproheptadine Hydrochloride, by gender? *:

female:

  1. Abscess jaw (tooth abscess or root abscess)
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Dysgeusia (disorder of the sense of taste)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Emotional distress
  6. Face oedema (swelling of face)
  7. Gingival swelling (gums swelling)
  8. Hyperplasia (enlargement of an organ or tissue)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Impaired healing

male:

n/a

What are the common drug interactions of Demerol and Cyproheptadine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Abscess jaw (tooth abscess or root abscess)
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Dysgeusia (disorder of the sense of taste)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Emotional distress
  6. Face oedema (swelling of face)
  7. Gingival swelling (gums swelling)
  8. Hyperplasia (enlargement of an organ or tissue)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Impaired healing

What are the existing conditions these people have? *

  1. Stress And Anxiety: 15 people, 100.00%
  2. Metastases To Bone (cancer spreads to bone): 15 people, 100.00%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 100.00%
  4. Breast Cancer: 15 people, 100.00%
  5. Bone Pain: 15 people, 100.00%
  6. Breast Cancer Metastatic: 6 people, 40.00%
  7. Colon Cancer: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Demerol and Cyproheptadine hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Demerol and Cyproheptadine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyproheptadine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Demerol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyproheptadine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on meperidine hydrochloride and cyproheptadine hydrochloride (the active ingredients of Demerol and Cyproheptadine hydrochloride, respectively), and Demerol and Cyproheptadine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: