Denavir and Sertraline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Denavir (penciclovir sodium) and Sertraline (sertraline hydrochloride). Common drug interactions include hypoaesthesia among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Denavir and Sertraline. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Denavir?

Denavir has active ingredients of penciclovir sodium. eHealthMe is studying from 570 Denavir users. Check the latest studies of Denavir.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,305 Sertraline users. Check the latest studies of Sertraline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

19 people who take Denavir and Sertraline together, and have interactions are studied.

Denavir and Sertraline drug interactions.

What are the common drug interactions of Denavir and Sertraline, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Inability to crawl
Neuralgia (pain in one or more nerves)
Pain
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Emotional distress
Pain in extremity
Toothache (tooth pain)
Visual impairment

male:

Cardiac arrest
Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Renal failure (kidney dysfunction)

What are the common drug interactions of Denavir and Sertraline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Infection
Abdominal pain
General physical health deterioration (weak health status)
Injury
Uterine perforation (accidental puncture of the uterus)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)

50-59:

Alopecia (absence of hair from areas of the body)
Blood magnesium increased
Burning sensation
Muscle twitching
Myalgia (muscle pain)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Muscle spasms (muscle contraction)
Hypoaesthesia (reduced sense of touch or sensation)
Inability to crawl
Neuralgia (pain in one or more nerves)

60+:

Candiduria (candida in urine)
Chronic kidney disease
Cardiomyopathy (weakening of the heart muscle)
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Hyperkalaemia (damage to or disease of the kidney)
Pathogen resistance
Renal failure (kidney dysfunction)
Asthenia (weakness)
Atrioventricular block second degree (heart block second degree)
Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 42.11%
Indigestion: 7 people, 36.84%
Sleep Disorder: 6 people, 31.58%
Osteoporosis (bones weak and more likely to break): 6 people, 31.58%
Insomnia (sleeplessness): 6 people, 31.58%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 21.05%
Infection: 2 people, 10.53%
High Blood Cholesterol: 2 people, 10.53%
Birth Control: 2 people, 10.53%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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