Desloratadine and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Desloratadine (desloratadine) and Oxycodone (oxycodone hydrochloride). Common drug interactions include wheezing among females and muscle atrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Desloratadine and Oxycodone. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Desloratadine?

Desloratadine has active ingredients of desloratadine. It is often used in allergies. eHealthMe is studying from 4,207 Desloratadine users. Check the latest studies of Desloratadine.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

59 people who take Desloratadine and Oxycodone together, and have interactions are studied.

Desloratadine and Oxycodone drug interactions.

What are the common drug interactions of Desloratadine and Oxycodone, by gender? *:

female:

Wheezing (a high-pitched whistling sound made while you breath)
Wound infection
Contusion (a type of hematoma of tissue in which capillaries)
Pruritus (severe itching of the skin)
Rash erythematous (redness of the skin)
Abdominal pain upper
Angioedema (rapid swelling of the dermis)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased

male:

Muscle atrophy (a decrease in the mass of the muscle)
Myopathy (a muscular disease in which the muscle fibres do not function)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal discomfort
Bone density decreased
Deformity (disfigurement)
Drug ineffective
Dyspepsia (indigestion)
Emotional distress
Fall

What are the common drug interactions of Desloratadine and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Decreased appetite
Nausea (feeling of having an urge to vomit)

20-29:

Abdominal pain
Weight decreased
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Malaise (a feeling of general discomfort or uneasiness)
Urinary tract infection
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Deformity (disfigurement)
Gallbladder disorder
Injury

30-39:

Cardiac arrest
Sudden cardiac death

40-49:

Joint range of motion decreased (disease of joint movement)
Mass
Osteopenia (a condition where bone mineral density is lower than normal)
Radius fracture
Arthralgia (joint pain)
Dysphagia (a condition in which swallowing is difficult or painful)
Dysstasia (difficulty in standing)
Gait disturbance
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)

50-59:

Arthralgia (joint pain)
Asthenia (weakness)
Balance disorder
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Crying
Depression
Fatigue (feeling of tiredness)
Infection
Memory impairment
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

Muscle atrophy (a decrease in the mass of the muscle)
Myopathy (a muscular disease in which the muscle fibres do not function)
Abdominal discomfort
Diarrhoea
Drug ineffective
Dyspepsia (indigestion)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Vomiting
Wound infection

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 10.17%
Multiple Myeloma (cancer of the plasma cells): 6 people, 10.17%
Indigestion: 5 people, 8.47%
Urinary Tract Infection: 4 people, 6.78%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.78%
High Blood Pressure: 4 people, 6.78%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 4 people, 6.78%
Thyroid Diseases: 3 people, 5.08%
Nausea And Vomiting: 3 people, 5.08%
Mantle Cell Lymphoma Stage Iv (cancer of lymphocytes, a type of white blood cell, spreads to other part of body): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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