Serzone and Exidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Exidine (chlorhexidine gluconate). Common drug interactions include eating disorder among females and paraesthesia among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Exidine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

26 people who take Serzone and Exidine together, and have interactions are studied.

What are the common drug interactions of Serzone and Exidine, by gender? *:

female:

Eating disorder
Fall
Feeling drunk
Impaired driving ability
Limb injury
Loss of consciousness
Post-traumatic stress disorder
Psychiatric symptom
Road traffic accident
Somnambulism (sleep walking)

male:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal pain upper
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Constipation
Decreased interest
Deformity (disfigurement)
Diarrhoea
Dysaesthesia (abnormal sensation)
Dyspnoea (difficult or laboured respiration)
Emotional distress

What are the common drug interactions of Serzone and Exidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac disorder
Chest pain
Cystitis (inflammation of the wall of the bladder)
Gingivitis (inflammation of gums)
Hyperglycaemia (high blood sugar)
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Oral pain
Tooth infection
Toothache (tooth pain)

40-49:

n/a

50-59:

Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood cholesterol increased
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiac valve abscess (pus containing infection of heart valve)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Conjunctivitis (pink eye)

60+:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal pain upper
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Asthenia (weakness)
Balance disorder
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Blood cholesterol increased
Blood testosterone decreased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 15 people, 57.69%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 11.54%
Insomnia (sleeplessness): 3 people, 11.54%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 11.54%
Bipolar Disorder (mood disorder): 3 people, 11.54%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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