Desyrel and Aimovig drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Aimovig (erenumab-aooe). Common drug interactions include dyspnoea among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Desyrel and Aimovig. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Aimovig?

Aimovig has active ingredients of erenumab-aooe. eHealthMe is studying from 49,930 Aimovig users. Check the latest studies of Aimovig.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

48 people who take Desyrel and Aimovig together, and have interactions are studied.

What are the common drug interactions of Desyrel and Aimovig, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Anuria (failure of the kidneys to produce urine)
Cough
Diarrhoea
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Migraine (headache)
Neovascularisation (development of tiny, abnormal, leaky blood vessels inside the eye)
Paradoxical drug reaction

male:

Cardiac arrest
Chest pain
Erythema (redness of the skin)
Oral disorder (mouth disease)
Pruritus (severe itching of the skin)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred

What are the common drug interactions of Desyrel and Aimovig, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Splenomegaly (enlargement of spleen)
Therapeutic response unexpected

40-49:

Anxiety
Asthenia (weakness)
Drug ineffective
Dry mouth
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Abdominal pain
Anuria (failure of the kidneys to produce urine)
Cough
Diarrhoea
Drug ineffective
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Migraine (headache)
Nausea (feeling of having an urge to vomit)

60+:

Drug ineffective
Abdominal pain
Neovascularisation (development of tiny, abnormal, leaky blood vessels inside the eye)
Paradoxical drug reaction
Weight decreased
Aphasia (damage to the parts of the brain that control language)
Drooling (drop saliva uncontrollably from the mouth)
Dyskinesia (abnormality or impairment of voluntary movement)
Incontinence (lack of moderation or self-control)
Myalgia (muscle pain)

What are the existing conditions these people have? *

Migraine (headache): 40 people, 83.33%
Nausea (feeling of having an urge to vomit): 12 people, 25.00%
Pain: 9 people, 18.75%
Muscle Spasms (muscle contraction): 5 people, 10.42%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 6.25%
Stress And Anxiety: 3 people, 6.25%
Nausea And Vomiting: 3 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%
Dyspnea (difficult or laboured breathing): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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