Desyrel and Revlimid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Revlimid (lenalidomide). Common drug interactions include large intestine perforation among females and leukoencephalopathy among males.
The phase IV clinical study analyzes what interactions people have when they take Desyrel and Revlimid. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.
What is Desyrel?
Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.
What is Revlimid?
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.
96 people who take Desyrel and Revlimid together, and have interactions are studied.

What are the common drug interactions of Desyrel and Revlimid, by gender? *:
female:
- Large intestine perforation (hole in large intestine)
- Pelvic abscess
- Rash
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Thrombocytopenia (decrease of platelets in blood)
- Gingival disorder (gum disease)
- Tooth disorder (tooth disease)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Abdominal pain upper
- Blood glucose increased
male:
- Leukoencephalopathy (disease of the white matter in the brain)
- Dementia (madness)
- Acetabulum fracture (socket of the hip joint- fracture)
- Lung neoplasm (tumour of lung)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Back pain
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Disease complication
What are the common drug interactions of Desyrel and Revlimid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Lethargy (tiredness)
- Muscle spasms (muscle contraction)
- Myalgia (muscle pain)
- Abdominal pain
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Pulmonary mass
50-59:
- Gastritis (inflammation of stomach)
- Cyst (a closed sac)
- Acetabulum fracture (socket of the hip joint- fracture)
- Lung neoplasm (tumour of lung)
- Nausea (feeling of having an urge to vomit)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Disease complication
- Encephalitis (inflammation of the brain)
- Encephalitis viral (inflammation of the brain due to viral infection)
60+:
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Dementia (madness)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Back pain
- Neuropathy peripheral (surface nerve damage)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Fall
- Impaired healing
- Pyrexia (fever)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 21 people, 21.88%
- Pain: 16 people, 16.67%
- Sleep Disorder: 8 people, 8.33%
- Nausea And Vomiting: 8 people, 8.33%
- Dyspnea (difficult or laboured breathing): 8 people, 8.33%
- Constipation: 8 people, 8.33%
- Headache (pain in head): 6 people, 6.25%
- Cardiac Failure: 6 people, 6.25%
- Wheezing (a high-pitched whistling sound made while you breath): 5 people, 5.21%
- Stress And Anxiety: 5 people, 5.21%
* Approximation only. Some reports may have incomplete information.
Do you take Desyrel and Revlimid?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Desyrel and Revlimid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Desyrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Revlimid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Desyrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revlimid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on trazodone hydrochloride and lenalidomide (the active ingredients of Desyrel and Revlimid, respectively), and Desyrel and Revlimid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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