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Metformin and Beta 2 microglobulin increased - a phase IV clinical study of FDA data

Summary:

Beta 2 microglobulin increased is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are male, 50-59 old, also take Glucophage, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Beta 2 microglobulin increased when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Beta 2 microglobulin increased?

Beta 2 microglobulin increased is found to be associated with 157 drugs and 190 conditions by eHealthMe. Check the latest studies of Beta 2 microglobulin increased.

On Jul, 11, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 11 people (0.0%) have Beta 2 microglobulin increased.

Could Metformin cause Beta 2 microglobulin increased?

Among these 11 people:

What is the gender of people who have Beta 2 microglobulin increased when taking Metformin? *

  • female: 9.09 %
  • male: 90.91 %

What is the age of people who have Beta 2 microglobulin increased when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 90 %
  • 60+: 0.0 %

What are other drugs people take besides Metformin? *

  1. Glucophage: 8 people, 72.73%
  2. Zometa: 7 people, 63.64%
  3. Lovenox: 7 people, 63.64%
  4. Novolog: 7 people, 63.64%
  5. Neurontin: 7 people, 63.64%
  6. Ativan: 7 people, 63.64%
  7. Ms Contin: 7 people, 63.64%
  8. Miralax: 7 people, 63.64%
  9. Micro-K: 7 people, 63.64%
  10. Bactrim: 7 people, 63.64%

What are other side effects people have besides Beta 2 microglobulin increased? *

  1. White Blood Cell Count Decreased: 8 people, 72.73%
  2. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 8 people, 72.73%
  3. Joint Pain: 8 people, 72.73%
  4. Fatigue (feeling of tiredness): 8 people, 72.73%
  5. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 8 people, 72.73%
  6. Haematochezia (passage of stools containing blood): 7 people, 63.64%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 63.64%
  8. Neuralgia (pain in one or more nerves): 7 people, 63.64%
  9. Myelitis Transverse (a neurological condition consisting of an inflammatory process of the spinal cord): 7 people, 63.64%
  10. Mucosal Inflammation (infection of mucous membrane): 7 people, 63.64%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 7 people, 63.64%
  2. Psoriasis (immune-mediated disease that affects the skin): 2 people, 18.18%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
  4. Pain: 1 person, 9.09%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
  6. Constipation: 1 person, 9.09%
  7. Birth Control: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Beta 2 microglobulin increased?

- Check whether Beta 2 microglobulin increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Beta 2 microglobulin increased treatments and more:

How severe was Beta 2 microglobulin increased and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Beta 2 microglobulin increased:

Browse all the conditions that are associated with Beta 2 microglobulin increased:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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