Desyrel and Temovate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Temovate (clobetasol propionate). Common drug interactions include malaise among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Desyrel and Temovate. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Temovate?

Temovate has active ingredients of clobetasol propionate. eHealthMe is studying from 1,392 Temovate users. Check the latest studies of Temovate.



On Jul, 15, 2026

26 people who take Desyrel and Temovate together, and have interactions are studied.

Desyrel and Temovate drug interactions.

What are the common drug interactions of Desyrel and Temovate, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Pain
  3. Pain in extremity
  4. Abdominal pain
  5. Abdominal pain upper
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Anxiety
  8. Asthenia (weakness)
  9. Body temperature increased
  10. Burning sensation

male:

  1. Back pain
  2. Constipation
  3. Visual impairment
  4. Abdominal discomfort
  5. Anxiety
  6. Blindness unilateral
  7. Blood glucose increased
  8. Cataract (clouding of the lens inside the eye)
  9. Chest pain
  10. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the common drug interactions of Desyrel and Temovate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  3. Headache (pain in head)
  4. Hyperglycaemia (high blood sugar)
  5. Myalgia (muscle pain)
  6. Paranasal sinus hypersecretion
  7. Pulmonary function test decreased
  8. Sinus congestion (blockage of sinus)

40-49:

  1. Acute respiratory distress syndrome
  2. Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

  1. Acute respiratory distress syndrome
  2. Chronic kidney disease
  3. Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

60+:

  1. Constipation
  2. Faecaloma (hard mass of fecal matter)
  3. Blindness unilateral
  4. Blood glucose increased
  5. Body temperature increased
  6. Cataract (clouding of the lens inside the eye)
  7. Chest pain
  8. Colitis (inflammation of colon)
  9. Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)
  10. Diabetic retinopathy (damage to the retina caused by complications of diabetes)

What are the existing conditions these people have? *

  1. Pain: 14 people, 53.85%
  2. Depression: 7 people, 26.92%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 26.92%
  4. Psoriasis (immune-mediated disease that affects the skin): 6 people, 23.08%
  5. High Blood Pressure: 6 people, 23.08%
  6. Constipation: 5 people, 19.23%
  7. Cardiac Failure Congestive: 5 people, 19.23%
  8. Neuralgia (pain in one or more nerves): 4 people, 15.38%
  9. Neuropathy Peripheral (surface nerve damage): 4 people, 15.38%
  10. Oedema (fluid collection in tissue): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Desyrel and Temovate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Desyrel and Temovate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Desyrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Temovate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Desyrel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Temovate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trazodone hydrochloride and clobetasol propionate (the active ingredients of Desyrel and Temovate, respectively), and Desyrel and Temovate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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