Argatroban and Bivalirudin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Argatroban (argatroban) and Bivalirudin (bivalirudin). Common drug interactions include pulmonary embolism among females and jugular vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Argatroban and Bivalirudin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Argatroban?

Argatroban has active ingredients of argatroban. eHealthMe is studying from 1,847 Argatroban users. Check the latest studies of Argatroban.

What is Bivalirudin?

Bivalirudin has active ingredients of bivalirudin. eHealthMe is studying from 908 Bivalirudin users. Check the latest studies of Bivalirudin.

On Jul, 15, 2026

38 people who take Argatroban and Bivalirudin together, and have interactions are studied.

Argatroban and Bivalirudin drug interactions.

What are the common drug interactions of Argatroban and Bivalirudin, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Abdominal pain
Anxiety
Hypertension (high blood pressure)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Jugular vein thrombosis (clot in jugular vein)
Venous thrombosis limb (blood clot that forms in a vein in the limb)
Cross sensitivity reaction
Platelet count decreased
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Incision site haemorrhage (bleeding from incision site)
Anaemia (lack of blood)
Disease progression
Heparin-induced thrombocytopenia
Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Argatroban and Bivalirudin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pulmonary embolism (blockage of the main artery of the lung)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Abdominal pain
Anxiety
Hypertension (high blood pressure)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Respiratory failure (inadequate gas exchange by the respiratory system)

20-29:

Cardiac tamponade (fluid accumulates in heart covering)
Pericardial haemorrhage (bleeding into the heart)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)

30-39:

n/a

40-49:

Jugular vein thrombosis (clot in jugular vein)
Venous thrombosis limb (blood clot that forms in a vein in the limb)
Coagulopathy (blood's ability to clot is impaired)
Drug ineffective
Drug resistance (reduction in effectiveness of a drug)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Mediastinal haemorrhage (bleeding in mediastinum)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dry gangrene (diminished blood supply due to vascular problems)
Gangrene (body tissue dies)

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Heparin-induced thrombocytopenia
Abdominal pain
Disease progression
Haematochezia (passage of stools containing blood)
Thrombosis (formation of a blood clot inside a blood vessel)
Drug ineffective
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Pulmonary embolism (blockage of the main artery of the lung)
Acute myocardial infarction (acute heart attack)

60+:

Cross sensitivity reaction
Platelet count decreased
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Anaemia (lack of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

Heparin-Induced Thrombocytopenia: 9 people, 23.68%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 15.79%
Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 13.16%
Vena Cava Thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart): 4 people, 10.53%
Renal Vein Thrombosis (blood clot in renal vein): 4 people, 10.53%
Thrombocytopenia (decrease of platelets in blood): 2 people, 5.26%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 5.26%
Chest Pain: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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