Pentam and Guaifenesin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentam (pentamidine isethionate) and Guaifenesin (guaifenesin). Common drug interactions include hypoxia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Pentam and Guaifenesin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Pentam?

Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

On Jul, 15, 2026

16 people who take Pentam and Guaifenesin together, and have interactions are studied.

Pentam and Guaifenesin drug interactions.

What are the common drug interactions of Pentam and Guaifenesin, by gender? *:

female:

Hypoxia (low oxygen in tissues)
Infection
Platelet count decreased
Pneumonia
Diabetes mellitus inadequate control
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Acute respiratory failure
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Aspergillosis (an infection caused by a fungus called aspergillus)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

male:

Diarrhoea
Renal failure (kidney dysfunction)
Contusion (a type of hematoma of tissue in which capillaries)
Drug maladministration
Epistaxis (bleed from the nose)
Face oedema (swelling of face)
Fall
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the common drug interactions of Pentam and Guaifenesin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

n/a

30-39:

n/a

40-49:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Blood creatinine increased
Cardiac ventricular disorder (ventricular dysfunction of heart)
Conduction disorder (serious disorder of the heart not responses proper to impulses)
Constipation
Culture urine positive
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Electrocardiogram st-t change

50-59:

Acute respiratory failure
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Aspergillosis (an infection caused by a fungus called aspergillus)
Blood disorder
Bradycardia (abnormally slow heart action)
Cardiac arrest
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Death
Drug maladministration

60+:

Diarrhoea
Blood bilirubin increased
Fall
Fatigue (feeling of tiredness)
Malignant neoplasm progression (cancer tumour came back)
Muscle spasms (muscle contraction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Pneumonia
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the existing conditions these people have? *

Constipation: 5 people, 31.25%
Pain: 5 people, 31.25%
Hypokalemia (low potassium): 4 people, 25.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 25.00%
Rashes (redness): 3 people, 18.75%
Multiple Myeloma (cancer of the plasma cells): 3 people, 18.75%
Pneumonia: 3 people, 18.75%
Leukaemia (blood or bone marrow cancer): 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Pentam and Guaifenesin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously