Renvela and Lexiva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renvela (sevelamer carbonate) and Lexiva (fosamprenavir calcium). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Renvela and Lexiva. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Renvela?

Renvela has active ingredients of sevelamer carbonate. eHealthMe is studying from 10,923 Renvela users. Check the latest studies of Renvela.

What is Lexiva?

Lexiva has active ingredients of fosamprenavir calcium. It is often used in hiv infection. eHealthMe is studying from 1,408 Lexiva users. Check the latest studies of Lexiva.

On Jul, 15, 2026

14 people who take Renvela and Lexiva together, and have interactions are studied.

What are the common drug interactions of Renvela and Lexiva, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Renal disorder (kidney disease)
Blood creatinine increased
Fatigue (feeling of tiredness)
Quality of life decreased
Bone density decreased

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteopenia (a condition where bone mineral density is lower than normal)
Quality of life decreased
Anaemia (lack of blood)
Nephrolithiasis (calculi in the kidneys)
Renal cyst (kidney cyst)
Renal transplant
Emotional distress
Pain

What are the common drug interactions of Renvela and Lexiva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Decreased activity
Emotional distress
Pain
Quality of life decreased
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Decreased activity
Emotional distress
Pain
Quality of life decreased
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Blood creatinine increased

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Fatigue (feeling of tiredness)
Quality of life decreased
Renal failure (kidney dysfunction)
Chronic kidney disease
Impaired work ability
Mobility decreased (ability to move is reduced)

40-49:

Blood creatinine increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Skeletal injury (bone and supporting muscle injury)
Anaemia of chronic disease
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Renal transplant
Anxiety
Emotional distress
Fatigue (feeling of tiredness)
Pain

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Pain: 4 people, 28.57%
High Blood Pressure: 4 people, 28.57%
Rickets (softening of bones): 3 people, 21.43%
Arrhythmias (irregular heartbeat): 3 people, 21.43%
Inflammation: 3 people, 21.43%
Infection: 3 people, 21.43%
Blood Calcium Decreased: 3 people, 21.43%
Blood Potassium Decreased: 3 people, 21.43%
Chest Pain: 3 people, 21.43%
Cough: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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