Detrol la and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Detrol la (tolterodine tartrate) and Melatonin (melatonin). Common drug interactions include femur fracture among females and ejaculation failure among males.

The phase IV clinical study analyzes what interactions people have when they take Detrol la and Melatonin. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Detrol la?

Detrol la has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 13,358 Detrol la users. Check the latest studies of Detrol la.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.



On Jul, 12, 2026

71 people who take Detrol la and Melatonin together, and have interactions are studied.

Detrol la and Melatonin drug interactions.

What are the common drug interactions of Detrol La and Melatonin, by gender? *:

female:

  1. Femur fracture
  2. Fracture displacement
  3. Gait disturbance
  4. Head injury
  5. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  6. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  7. Hip fracture
  8. Hospitalisation
  9. Hyperhidrosis (abnormally increased sweating)
  10. Hypertension (high blood pressure)

male:

  1. Ejaculation failure
  2. Hypertension (high blood pressure)
  3. Erectile dysfunction
  4. Facial bones fracture (bone fracture of face)
  5. Fatigue (feeling of tiredness)
  6. Hyperkeratosis (thickening of the outer layer of the skin)
  7. Hypersensitivity
  8. Rash
  9. Urinary retention (the inability to completely or partially empty the bladder)
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Detrol La and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Bedridden
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  3. Cystitis (inflammation of the wall of the bladder)
  4. Dizziness
  5. Fall
  6. Joint injury
  7. Micturition urgency (urgency to pass the urine)
  8. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Muscle spasms (muscle contraction)
  10. Neuritis (inflammation of nerve)

50-59:

  1. Skin infection
  2. Splenic rupture
  3. Thoracic vertebral fracture
  4. Traumatic liver injury
  5. Body mass index increased
  6. Concussion (short loss of normal brain function in response to a head injury)
  7. Drug hypersensitivity
  8. Drug ineffective
  9. Fall
  10. Head injury

60+:

  1. Fall
  2. Abdominal abscess (collection of pus in abdomen)
  3. Upper respiratory tract infection
  4. Dyspnoea (difficult or laboured respiration)
  5. Erythema (redness of the skin)
  6. Peripheral swelling
  7. Skin discolouration (change of skin colour)
  8. Skin lesion
  9. Abdominal wall cyst (abnormal membranous sac containing a gaseous, liquid, or semisolid substance on abdominal wall)
  10. Haemophilus infection (bacterial infection by haemophilus influenzae)

What are the existing conditions these people have? *

  1. Pain: 15 people, 21.13%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 16.90%
  3. Nausea (feeling of having an urge to vomit): 11 people, 15.49%
  4. Sleep Disorder: 9 people, 12.68%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 11.27%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.86%
  7. Headache (pain in head): 7 people, 9.86%
  8. Migraine (headache): 5 people, 7.04%
  9. Urinary Tract Infection: 5 people, 7.04%
  10. Depression: 5 people, 7.04%

* Approximation only. Some reports may have incomplete information.

Do you take Detrol la and Melatonin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Detrol la and Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Detrol la:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Detrol la and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melatonin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tolterodine tartrate and melatonin (the active ingredients of Detrol la and Melatonin, respectively), and Detrol la and Melatonin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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