Detrol and Bactrim ds drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Detrol (tolterodine tartrate) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include osteonecrosis of jaw among females and tremor among males.
The phase IV clinical study analyzes what interactions people have when they take Detrol and Bactrim ds. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.
What is Detrol?
Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.
What is Bactrim ds?
Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.
60 people who take Detrol and Bactrim ds together, and have interactions are studied.

What are the common drug interactions of Detrol and Bactrim Ds, by gender? *:
female:
- Osteonecrosis of jaw (death of bone of jaw)
- Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)
- Renal failure chronic (long lasting kidney dysfunction)
- Rib fracture
- Sinus headache (headache caused by sinus infections)
- Sinusitis (inflammation of sinus)
- Spinal column stenosis (narrowing of spinal column)
- Spinal compression fracture (fracture due to spinal compression on bone)
- Toothache (tooth pain)
- Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
male:
- Tremor (trembling or shaking movements in one or more parts of your body)
- Fatigue (feeling of tiredness)
- Stress
- Suicidal ideation
- Weight increased
- Muscle spasms (muscle contraction)
- Abdominal discomfort
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Chills (felling of cold)
- Drug ineffective
What are the common drug interactions of Detrol and Bactrim Ds, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Headache (pain in head)
- Muscle spasms (muscle contraction)
- Rash
- Fall
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Abdominal pain
- Accelerated hypertension (significant hypertension)
- Back pain
- Cardiac murmur (an heart sound in valve abnormality)
- Death
50-59:
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Dizziness
- Drug effect decreased
- Dysphasia (language disorder marked by deficiency in the generation of speech)
- Fatigue (feeling of tiredness)
- Haemorrhage (bleeding)
- Hypotonia (low muscle tone)
- Lethargy (tiredness)
- Muscle spasms (muscle contraction)
- Muscle tightness
60+:
- Cough
- Drug ineffective
- Sneezing
- Tooth abscess (pus formation in tooth)
- Tooth loss
- Dyspnoea (difficult or laboured respiration)
- Malaise (a feeling of general discomfort or uneasiness)
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Fall
What are the existing conditions these people have? *
- Pain: 13 people, 21.67%
- Incontinence (lack of moderation or self-control): 9 people, 15.00%
- Muscle Spasms (muscle contraction): 7 people, 11.67%
- Itching: 7 people, 11.67%
- Hypersensitivity: 7 people, 11.67%
- Depression: 7 people, 11.67%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 7 people, 11.67%
- High Blood Cholesterol: 6 people, 10.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 10.00%
- Sleep Disorder: 5 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Detrol and Bactrim ds?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Detrol (28,669 reports)
- Bactrim ds (17,027 reports)
Browse all drug interactions of Detrol and Bactrim ds:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Detrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bactrim ds:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Detrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bactrim ds and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tolterodine tartrate and sulfamethoxazole; trimethoprim (the active ingredients of Detrol and Bactrim ds, respectively), and Detrol and Bactrim ds (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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