Lyrica and Spasmodic dysphonia - a phase IV clinical study of FDA data

Summary:

Spasmodic dysphonia is reported as a side effect among people who take Lyrica (pregabalin), especially for people who are female, 60+ old, also take Prilosec, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Spasmodic dysphonia when taking Lyrica. It is created by eHealthMe based on reports of 255,839 people who have side effects when taking Lyrica from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Spasmodic dysphonia?

Spasmodic dysphonia (a voice disorder characterized by involuntary movements or spasms of one or more muscles of the larynx) is found to be associated with 50 drugs and 182 conditions by eHealthMe. Check the latest studies of Spasmodic dysphonia.

On Jul, 19, 2026

255,839 people reported to have side effects when taking Lyrica.
Among them, 13 people (0.01%) have Spasmodic dysphonia.

Among these 13 people:

What is the gender of people who have Spasmodic dysphonia when taking Lyrica? *

female: 100 %
male: 0.0 %

What is the age of people who have Spasmodic dysphonia when taking Lyrica? *

What are other drugs people take besides Lyrica? *

What are other side effects people have besides Spasmodic dysphonia? *

Swallowing Difficulty: 8 people, 61.54%
Swelling Face: 8 people, 61.54%
Gums - Swollen: 7 people, 53.85%
Speech Impairment (Adult) (inability to speak (adult)): 7 people, 53.85%
Parkinson's Disease: 5 people, 38.46%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 30.77%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 30.77%
Sleep Disorder: 4 people, 30.77%
Balance Disorder: 4 people, 30.77%
Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 30.77%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 30.77%
Post-Traumatic Stress Disorder: 1 person, 7.69%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Spasmodic dysphonia?

- Check whether Spasmodic dysphonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lyrica:

Lyrica (261,646 reports)

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spasmodic dysphonia:

Spasmodic dysphonia (50 drugs)

Browse all the conditions that are associated with Spasmodic dysphonia:

Spasmodic dysphonia (182 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.