Detrol and Pacerone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Detrol (tolterodine tartrate) and Pacerone (amiodarone hydrochloride). Common drug interactions include hypotension among females and cardiac arrest among males.
The phase IV clinical study analyzes what interactions people have when they take Detrol and Pacerone. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Detrol?
Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.
What is Pacerone?
Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.
39 people who take Detrol and Pacerone together, and have interactions are studied.

What are the common drug interactions of Detrol and Pacerone, by gender? *:
female:
- Hypotension (abnormally low blood pressure)
- Hypertension (high blood pressure)
- Pulmonary oedema (fluid accumulation in the lungs)
- Blood cholesterol increased
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Pneumonia
- Acute myocardial infarction (acute heart attack)
- Anaemia (lack of blood)
- Anxiety
male:
- Cardiac arrest
- Hypotension (abnormally low blood pressure)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Renal failure (kidney dysfunction)
- Temperature intolerance (inability to go in temperature)
- Vertigo
- Confusional state
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Muscular weakness (muscle weakness)
- Pain in extremity
What are the common drug interactions of Detrol and Pacerone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Cardiac arrest
- Cardiac failure congestive
- Atrioventricular block complete (heart block complete)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Sinusitis (inflammation of sinus)
- Anaemia (lack of blood)
- Abasia (inability to walk)
- Arthralgia (joint pain)
- Balance disorder
- Delirium (wild excitement)
What are the existing conditions these people have? *
- Cardiac Failure Congestive: 9 people, 23.08%
- High Blood Pressure: 6 people, 15.38%
- Stress And Anxiety: 6 people, 15.38%
- Arrhythmias (irregular heartbeat): 5 people, 12.82%
- Depression: 4 people, 10.26%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.26%
- Thyroid Diseases: 4 people, 10.26%
- Sleep Disorder: 4 people, 10.26%
- Hypersensitivity: 3 people, 7.69%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Detrol and Pacerone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Detrol and Pacerone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Detrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pacerone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Detrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pacerone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on tolterodine tartrate and amiodarone hydrochloride (the active ingredients of Detrol and Pacerone, respectively), and Detrol and Pacerone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Zolpidem cause Hyperammonaemia? - 26 seconds ago
- Could Zyrtec cause Ear Disorder? - 37 seconds ago
- Drug interactions of Midostaurin and Xospata - 39 seconds ago
- Could Calcitriol cause Intervertebral Disc Protrusion? - a minute ago
- Drug interactions of Paracetamol and Gilenya - a minute ago
- Xanax vs. Lioresal, side effect and effectiveness comparison - a minute ago
- Drug interactions of Orencia and Naproxen Sodium - 2 minutes ago
- Drug interactions of Charcoal and Melatonin - 2 minutes ago
- Could Ergocalciferol cause Sputum Discolored? - 2 minutes ago
- Could Tivicay cause Mania? - 2 minutes ago