Dexedrine and Estrace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexedrine (dextroamphetamine sulfate) and Estrace (estradiol). Common drug interactions include migraine among females.

The phase IV clinical study analyzes what interactions people have when they take Dexedrine and Estrace. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Dexedrine?

Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.

On Jul, 06, 2026

72 people who take Dexedrine and Estrace together, and have interactions are studied.

Dexedrine and Estrace drug interactions.

What are the common drug interactions of Dexedrine and Estrace, by gender? *:

female:

Migraine (headache)
Drug ineffective
Muscular weakness (muscle weakness)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Back pain
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Thrombosis (formation of a blood clot inside a blood vessel)
Vomiting

male:

n/a

What are the common drug interactions of Dexedrine and Estrace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Back pain
Blood magnesium decreased
Blood potassium decreased
Decreased appetite
Diarrhoea
Drug detoxification
Eye inflammation
Hyperthyroidism (over activity of the thyroid gland)
Hypoacusis (loss of hearing)

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Blood pressure increased
Peripheral swelling
Sinusitis (inflammation of sinus)
Sleep attacks
Somnolence (a state of near-sleep, a strong desire for sleep)
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Vomiting
Fatigue (feeling of tiredness)
Inflammation
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Therapeutic response decreased (less preventive response)
Weight increased
Conjunctivitis (pink eye)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 39 people, 54.17%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 20.83%
Nausea (feeling of having an urge to vomit): 6 people, 8.33%
Depression: 6 people, 8.33%
Uveitis (inflammation of the uvea): 5 people, 6.94%
Drowsiness: 5 people, 6.94%

* Approximation only. Some reports may have incomplete information.

Do you take Dexedrine and Estrace?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously