Dexedrine and Vytorin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dexedrine (dextroamphetamine sulfate) and Vytorin (ezetimibe; simvastatin). Common drug interactions include hospitalisation among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Dexedrine and Vytorin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Dexedrine?
Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.
What is Vytorin?
Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.
16 people who take Dexedrine and Vytorin together, and have interactions are studied.

What are the common drug interactions of Dexedrine and Vytorin, by gender? *:
female:
- Hospitalisation
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Cardiovascular disorder (heart diseases)
- Emotional distress
- Injury
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Neuropathy peripheral (surface nerve damage)
- Pain
male:
- Fall
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Dizziness
- Ejection fraction decreased (systolic heart failure)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Heart rate increased
- Hypotension (abnormally low blood pressure)
- Influenza like illness
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the common drug interactions of Dexedrine and Vytorin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Body height increased
- Weight increased
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Confusional state
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dizziness
- Ejection fraction decreased (systolic heart failure)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Fall
- Heart rate increased
- Hypotension (abnormally low blood pressure)
- Influenza like illness
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
60+:
- Chronic kidney disease
- Clavicle fracture
- Fall
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Renal failure (kidney dysfunction)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 56.25%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 31.25%
- High Blood Pressure: 2 people, 12.50%
- Pain: 2 people, 12.50%
- Neuralgia (pain in one or more nerves): 2 people, 12.50%
- Depression: 1 person, 6.25%
- Asthma: 1 person, 6.25%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.25%
- Bipolar Disorder (mood disorder): 1 person, 6.25%
- Birth Control: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Dexedrine and Vytorin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dexedrine and Vytorin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dexedrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vytorin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexedrine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vytorin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dextroamphetamine sulfate and ezetimibe; simvastatin (the active ingredients of Dexedrine and Vytorin, respectively), and Dexedrine and Vytorin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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