Dexilant and Melphalan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexilant (dexlansoprazole) and Melphalan (melphalan). Common drug interactions include febrile neutropenia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Dexilant and Melphalan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

What is Melphalan?

Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.

On Jul, 21, 2026

19 people who take Dexilant and Melphalan together, and have interactions are studied.

Dexilant and Melphalan drug interactions.

What are the common drug interactions of Dexilant and Melphalan, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
Epistaxis (bleed from the nose)
Haemoglobin decreased
Platelet count decreased

male:

Febrile neutropenia (fever with reduced white blood cells)
Streptococcal bacteraemia (a bacterial infection of blood)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pyrexia (fever)
Viral upper respiratory tract infection
Anaemia (lack of blood)
Chest pain
Decreased appetite

What are the common drug interactions of Dexilant and Melphalan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Streptococcal bacteraemia (a bacterial infection of blood)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Pyrexia (fever)
Viral upper respiratory tract infection

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 13 people, 68.42%
Multiple Myeloma (cancer of the plasma cells): 6 people, 31.58%

* Approximation only. Some reports may have incomplete information.

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