Dexilant and Roxicodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexilant (dexlansoprazole) and Roxicodone (oxycodone hydrochloride). Common drug interactions include essential hypertension among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Dexilant and Roxicodone. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

On Jul, 26, 2026

73 people who take Dexilant and Roxicodone together, and have interactions are studied.

Dexilant and Roxicodone drug interactions.

What are the common drug interactions of Dexilant and Roxicodone, by gender? *:

female:

Essential hypertension (primary hypertension)
Libido decreased (loss of interest in sex)
Malignant melanoma (skin cancer rises from melancytes)
Menopausal symptoms
Obesity (having too much body fat)
Oedema peripheral (superficial swelling)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sensation of foreign body
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Swelling

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)
Thrombosis (formation of a blood clot inside a blood vessel)
Abdominal discomfort
Chest injury
Clavicle fracture
Drug intolerance (drug sensitivity)
Epistaxis (bleed from the nose)
Foot deformity (functional disability of foot)

What are the common drug interactions of Dexilant and Roxicodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

30-39:

Renal failure (kidney dysfunction)
Emotional disorder
Retinal dystrophy (progressive weakness and wasting of the retina)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal injury (kidney injury)
Anxiety
Arthralgia (joint pain)
Arthropathy
Blood creatine phosphokinase increased

40-49:

Chronic kidney disease
Sinusitis (inflammation of sinus)
Death
Septic shock (shock due to blood infection)
Burning sensation
Epistaxis (bleed from the nose)
Foot deformity (functional disability of foot)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasal discharge discolouration (change in colour of nasal discharge)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

50-59:

Libido decreased (loss of interest in sex)
Malignant melanoma (skin cancer rises from melancytes)
Menopausal symptoms
Nausea (feeling of having an urge to vomit)
Obesity (having too much body fat)
Oedema peripheral (superficial swelling)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sensation of foreign body
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Swelling

60+:

Fatigue (feeling of tiredness)
Cough
Arteriosclerosis (thickening and hardening of arteries)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)
Bacterial infection
Balance disorder
Benign prostatic hyperplasia (benign enlargement of the prostate)
Blood copper decreased
Blood thyroid stimulating hormone increased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 24.66%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 16.44%
High Blood Pressure: 10 people, 13.70%
Itching: 7 people, 9.59%
Stress And Anxiety: 7 people, 9.59%
Nausea (feeling of having an urge to vomit): 7 people, 9.59%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 9.59%
Hypersensitivity: 7 people, 9.59%
Migraine (headache): 6 people, 8.22%
Thermal Burn (burn by heat): 6 people, 8.22%

* Approximation only. Some reports may have incomplete information.

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