Dextroamphetamine sulfate and Ritalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dextroamphetamine sulfate (dextroamphetamine sulfate) and Ritalin (methylphenidate hydrochloride). Common drug interactions include abnormal dreams among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Dextroamphetamine sulfate and Ritalin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Dextroamphetamine sulfate?

Dextroamphetamine sulfate has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,013 Dextroamphetamine sulfate users. Check the latest studies of Dextroamphetamine sulfate.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.



On Jul, 19, 2026

13 people who take Dextroamphetamine sulfate and Ritalin together, and have interactions are studied.

Dextroamphetamine sulfate and Ritalin drug interactions.

What are the common drug interactions of Dextroamphetamine Sulfate and Ritalin, by gender? *:

female:

  1. Abnormal dreams
  2. Irritable bowel syndrome
  3. Stress
  4. Surgery
  5. Therapeutic response decreased (less preventive response)
  6. Abdominal pain
  7. Bladder spasm
  8. Cataract (clouding of the lens inside the eye)
  9. Cholecystitis (infection of gallbladder)
  10. Colour blindness (inability to view some colour)

male:

  1. Anxiety
  2. Blood pressure decreased
  3. Substance abuse
  4. Therapeutic response unexpected
  5. Drug ineffective
  6. Fatigue (feeling of tiredness)
  7. Impulsive behaviour
  8. Insomnia (sleeplessness)
  9. Irritability
  10. Learning disability (difficulty in learning)

What are the common drug interactions of Dextroamphetamine Sulfate and Ritalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Therapeutic response unexpected
  3. Vomiting
  4. Abdominal pain
  5. Cholecystitis (infection of gallbladder)
  6. Gallbladder pain
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nausea (feeling of having an urge to vomit)

40-49:

n/a

50-59:

  1. Abnormal dreams
  2. Irritable bowel syndrome
  3. Stress
  4. Surgery
  5. Therapeutic response decreased (less preventive response)

60+:

n/a

What are the existing conditions these people have? *

  1. High Blood Pressure: 4 people, 30.77%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
  3. Drowsiness: 3 people, 23.08%
  4. Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating): 3 people, 23.08%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 23.08%
  6. Irritable Bowel Syndrome: 2 people, 15.38%
  7. Back Pain: 1 person, 7.69%
  8. Bladder Spasm: 1 person, 7.69%
  9. Constipation: 1 person, 7.69%
  10. Visual Impairment: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dextroamphetamine sulfate and Ritalin:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dextroamphetamine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ritalin:

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Browse all interactions between Dextroamphetamine sulfate and drugs from A to Z:

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Browse all interactions between Ritalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dextroamphetamine sulfate and methylphenidate hydrochloride (the active ingredients of Dextroamphetamine sulfate and Ritalin, respectively), and Dextroamphetamine sulfate and Ritalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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