Diamox and Amoxicillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diamox (acetazolamide) and Amoxicillin (amoxicillin). Common drug interactions include blindness among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Diamox and Amoxicillin. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Diamox?

Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,712 Diamox users. Check the latest studies of Diamox.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,236 Amoxicillin users. Check the latest studies of Amoxicillin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

39 people who take Diamox and Amoxicillin together, and have interactions are studied.

Diamox and Amoxicillin drug interactions.

What are the common drug interactions of Diamox and Amoxicillin, by gender? *:

female:

Blindness
Blood glucose increased
Chest discomfort
Culture urine positive
Dyspepsia (indigestion)
Foot fracture
Headache (pain in head)
Neuropathy peripheral (surface nerve damage)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Rales (an abnormal respiratory sound characterized by fine crackles)

male:

Chronic kidney disease
Bone density decreased
Spinal fracture (fracture in one of vertebrae)
Confusional state
Death
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Multiple fractures
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Tooth loss

What are the common drug interactions of Diamox and Amoxicillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Altered state of consciousness (altered state of mind)
Hydrocephalus (water on the brain)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Subdural haematoma (blood collects between the skull and the surface of the brain)

10-19:

n/a

20-29:

Blindness
Headache (pain in head)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Visual acuity reduced (reduced clearness of vision)
Visual impairment

30-39:

Dyspnoea (difficult or laboured respiration)
Emotional distress
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cerebral venous thrombosis (clot in brains venous blood system)
Joint swelling
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pain in limb
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Bone density decreased
Bone loss
Depression
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Osteomalacia (softening of the bones due to a lack of vitamin d)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Pathological fracture (broken bone caused by disease)

50-59:

Pain
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
Viral infection
White blood cell count increased
Abdominal pain
Back pain
Blindness unilateral
Blood glucose increased
Cataract (clouding of the lens inside the eye)
Corneal abrasion (loss of the surface of cornea)

60+:

Vomiting
Cough
Cardiac failure congestive
Diarrhoea
Dizziness
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Escherichia infection (bacterial infection by escherichia coli)
Eye irritation
Fatigue (feeling of tiredness)
Headache (pain in head)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 20.51%
High Blood Pressure: 7 people, 17.95%
Depression: 5 people, 12.82%
Oedema (fluid collection in tissue): 4 people, 10.26%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 10.26%
High Blood Cholesterol: 3 people, 7.69%
Diabetes: 3 people, 7.69%
Drug Hypersensitivity: 3 people, 7.69%
Fluid Overload (too much fluid in the blood): 3 people, 7.69%
Pancreatic Necrosis (death of pancreas tissue in pancreas): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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