Diamox and Fluorouracil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diamox (acetazolamide) and Fluorouracil (fluorouracil). Common drug interactions include agranulocytosis among females and diverticular perforation among males.

The phase IV clinical study analyzes what interactions people have when they take Diamox and Fluorouracil. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Diamox?

Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

16 people who take Diamox and Fluorouracil together, and have interactions are studied.

Diamox and Fluorouracil drug interactions.

What are the common drug interactions of Diamox and Fluorouracil, by gender? *:

female:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Asthma
Dyspnoea (difficult or laboured respiration)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Acidosis (build-up of carbon dioxide in the blood)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood pressure decreased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

male:

Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Malaise (a feeling of general discomfort or uneasiness)
Anti-hbe antibody positive
Death
Gastric cancer (stomach cancer)
Hepatitis b
Hepatitis b surface antigen positive
Myelosuppression (a decrease in the production of blood cells)
Back pain

What are the common drug interactions of Diamox and Fluorouracil, by age (0-1 to 60+)? *:

0-1:

Myelosuppression (a decrease in the production of blood cells)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acidosis (build-up of carbon dioxide in the blood)
Blood pressure decreased
Hypokalaemia (low potassium)
Loss of consciousness

50-59:

Anti-hbe antibody positive
Hepatitis b
Hepatitis b surface antigen positive

60+:

Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Fatigue (feeling of tiredness)
General physical health deterioration (weak health status)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Malaise (a feeling of general discomfort or uneasiness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased

What are the existing conditions these people have? *

Oral Cancer (mouth cancer): 4 people, 25.00%
Metastases To Bone (cancer spreads to bone): 2 people, 12.50%
Insomnia (sleeplessness): 2 people, 12.50%
Gastritis Haemorrhagic (inflammation of stomach with bleeding): 2 people, 12.50%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 2 people, 12.50%
Constipation: 2 people, 12.50%
Cancer Pain: 2 people, 12.50%
Anal Cancer: 2 people, 12.50%
Gastric Cancer (stomach cancer): 1 person, 6.25%
Chemotherapy Cardiotoxicity Attenuation: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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