Diamox and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diamox (acetazolamide) and Wellbutrin (bupropion hydrochloride). Common drug interactions include respiratory failure among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Diamox and Wellbutrin. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Diamox?

Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,712 Diamox users. Check the latest studies of Diamox.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,115 Wellbutrin users. Check the latest studies of Wellbutrin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

58 people who take Diamox and Wellbutrin together, and have interactions are studied.

Diamox and Wellbutrin drug interactions.

What are the common drug interactions of Diamox and Wellbutrin, by gender? *:

female:

Respiratory failure (inadequate gas exchange by the respiratory system)
Rosacea (a skin condition that causes facial redness)
Urinary tract infection
Abdominal distension
Abdominal pain upper
Abnormal behaviour
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood cholesterol increased

male:

Dizziness
Acute respiratory failure
Renal failure chronic (long lasting kidney dysfunction)
Weight decreased
Anaemia (lack of blood)
Anaemia of chronic disease
Asthenia (weakness)
Blood pressure decreased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac failure congestive

What are the common drug interactions of Diamox and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Hypoglycaemia (deficiency of glucose in the bloodstream)
Ketoacidosis (high concentrations of ketone bodies in blood)
Cholecystitis acute (rapid infection of gallbladder)
Constipation
Diarrhoea
Dizziness
Drug ineffective
Fatigue (feeling of tiredness)

30-39:

Dizziness
Fatigue (feeling of tiredness)
Influenza like illness
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Papilloedema (optic disc swelling)
Vision blurred
Abdominal distension
Arthralgia (joint pain)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

40-49:

Confusional state
Asthenia (weakness)
Blood pressure decreased
Dizziness
Fall
Hypoglycaemia (deficiency of glucose in the bloodstream)
Post-traumatic stress disorder
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper

50-59:

Renal failure chronic (long lasting kidney dysfunction)
Weight decreased
Anaemia (lack of blood)
Anaemia of chronic disease
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Hypertensive heart disease
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Pancreatitis acute (sudden inflammation of pancreas)
Renal failure acute (rapid kidney dysfunction)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Headache (pain in head)
Rosacea (a skin condition that causes facial redness)
Urinary tract infection
Abdominal pain upper
Anaemia (lack of blood)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood cholesterol increased

What are the existing conditions these people have? *

Migraine (headache): 7 people, 12.07%
Stress And Anxiety: 5 people, 8.62%
High Blood Cholesterol: 4 people, 6.90%
Headache (pain in head): 4 people, 6.90%
Insomnia (sleeplessness): 3 people, 5.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.17%
Diabetes: 3 people, 5.17%
Bipolar Disorder (mood disorder): 3 people, 5.17%
Abdominal Pain: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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