Diclofenac and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diclofenac (diclofenac) and Daliresp (roflumilast). Common drug interactions include dyspnoea among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Diclofenac and Daliresp. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.



On Aug, 05, 2026

32 people who take Diclofenac and Daliresp together, and have interactions are studied.

Diclofenac and Daliresp drug interactions.

What are the common drug interactions of Diclofenac and Daliresp, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Productive cough
  3. Respiratory tract infection
  4. Sinusitis (inflammation of sinus)
  5. Chronic kidney disease
  6. Back pain
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Decreased appetite
  9. Drug ineffective
  10. Headache (pain in head)

male:

  1. Pain
  2. Asthenia (weakness)
  3. Lung disorder (lung disease)
  4. Obstruction
  5. Weight decreased
  6. Blood pressure fluctuation
  7. Lip infection (infection of lip)
  8. Respiratory tract congestion (blockage on respiratory system)
  9. Skin infection
  10. Arthralgia (joint pain)

What are the common drug interactions of Diclofenac and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

50-59:

  1. Bone density decreased
  2. Depressed mood
  3. Drug ineffective
  4. Emotional distress
  5. Joint injury
  6. Multiple fractures
  7. Osteoporosis (bones weak and more likely to break)
  8. Pain
  9. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  10. Pulmonary mass

60+:

  1. Respiratory tract infection
  2. Asthenia (weakness)
  3. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  4. Cardiac disorder
  5. Dyspnoea (difficult or laboured respiration)
  6. Lung disorder (lung disease)
  7. Sinusitis (inflammation of sinus)
  8. Weight decreased
  9. Blood pressure fluctuation
  10. Lip infection (infection of lip)

What are the existing conditions these people have? *

  1. Asthma: 8 people, 25.00%
  2. Immunodeficiency Common Variable: 6 people, 18.75%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 18.75%
  4. High Blood Cholesterol: 4 people, 12.50%
  5. Stress And Anxiety: 3 people, 9.38%
  6. Bacterial Infection: 3 people, 9.38%
  7. Chest Pain: 3 people, 9.38%
  8. Depression: 3 people, 9.38%
  9. Diabetes: 3 people, 9.38%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

Do you take Diclofenac and Daliresp?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diclofenac and Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diclofenac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diclofenac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daliresp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac and roflumilast (the active ingredients of Diclofenac and Daliresp, respectively), and Diclofenac and Daliresp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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