Diflucan and Feldene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diflucan (fluconazole) and Feldene (piroxicam). Common drug interactions include weight decreased among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Diflucan and Feldene. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.



On Jul, 04, 2026

23 people who take Diflucan and Feldene together, and have interactions are studied.

Diflucan and Feldene drug interactions.

What are the common drug interactions of Diflucan and Feldene, by gender? *:

female:

  1. Weight decreased
  2. Dizziness
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Hypertension (high blood pressure)
  5. Injury
  6. International normalised ratio increased
  7. Migraine (headache)
  8. Alopecia (absence of hair from areas of the body)
  9. Back pain
  10. Hypercholesterolaemia (high levels of cholesterol in the blood)

male:

  1. Drug hypersensitivity
  2. Delirium (wild excitement)
  3. Nausea (feeling of having an urge to vomit)
  4. Tongue discolouration (colour change of tongue)
  5. Tongue oedema (swelling of tongue)

What are the common drug interactions of Diflucan and Feldene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac disorder
  2. Migraine (headache)
  3. Type 1 diabetes mellitus
  4. Cardiac failure congestive
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Joint injury
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

n/a

40-49:

  1. Weight decreased
  2. International normalised ratio increased
  3. Cyst (a closed sac)
  4. Delirium (wild excitement)
  5. Hot flush (sudden feelings of heat)
  6. Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
  7. Laboratory test abnormal
  8. Loss of consciousness
  9. Migraine (headache)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Breast cancer in situ
  3. Drug ineffective
  4. Infection
  5. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  6. Skin disorder (skin disease)

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Hypokalaemia (low potassium)
  3. Muscle spasms (muscle contraction)
  4. Arthralgia (joint pain)
  5. Blood cholesterol increased
  6. Drug hypersensitivity
  7. Hypercholesterolaemia (high levels of cholesterol in the blood)
  8. Multiple injuries
  9. Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Ill-Defined Disorder: 3 people, 13.04%
  2. Post-Traumatic Stress Disorder: 2 people, 8.70%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Diflucan and Feldene?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diflucan and Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diflucan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diflucan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Feldene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluconazole and piroxicam (the active ingredients of Diflucan and Feldene, respectively), and Diflucan and Feldene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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