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Diflucan and Nuplazid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diflucan (fluconazole) and Nuplazid (pimavanserin tartrate). Common drug interactions include chest pain among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Diflucan and Nuplazid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

What is Nuplazid?

Nuplazid has active ingredients of pimavanserin tartrate. eHealthMe is studying from 47,103 Nuplazid users. Check the latest studies of Nuplazid.

On Jul, 12, 2026

13 people who take Diflucan and Nuplazid together, and have interactions are studied.

Diflucan and Nuplazid drug interactions.

What are the common drug interactions of Diflucan and Nuplazid, by gender? *:

female:

  1. Chest pain
  2. Confusional state
  3. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

male:

  1. Hallucination (an experience involving the perception of something not present)
  2. Feeding disorder (when children refuse to eat certain food groups)
  3. Decreased appetite
  4. Somatic delusion (false belief that one's bodily functioning, sensation, or appearance is grossly abnormal)
  5. Drug ineffective
  6. Nonspecific reaction (unspecified reaction)
  7. Pneumonia
  8. Parkinson's disease
  9. Weight decreased
  10. Delusion (a false belief or opinion)

What are the common drug interactions of Diflucan and Nuplazid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Confusional state
  2. Hallucination (an experience involving the perception of something not present)
  3. Hypersomnia (excessive daytime sleepiness (eds))
  4. Ill-defined disorder
  5. Insomnia (sleeplessness)
  6. Pneumonia
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Parkinson's disease
  9. Weight decreased
  10. Delusion (a false belief or opinion)

What are the existing conditions these people have? *

  1. Parkinson's Disease: 8 people, 61.54%
  2. Hallucinations (sensations that appear real but are created by your mind): 8 people, 61.54%
  3. Delusion (a false belief or opinion): 8 people, 61.54%
  4. Salivary Hypersecretion (excess saliva secretion): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Diflucan and Nuplazid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diflucan and Nuplazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diflucan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nuplazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diflucan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuplazid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluconazole and pimavanserin tartrate (the active ingredients of Diflucan and Nuplazid, respectively), and Diflucan and Nuplazid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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