Diflunisal and Ketoprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diflunisal (diflunisal) and Ketoprofen (ketoprofen). Common drug interactions include anxiety among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Diflunisal and Ketoprofen. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Diflunisal?

Diflunisal has active ingredients of diflunisal. eHealthMe is studying from 945 Diflunisal users. Check the latest studies of Diflunisal.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.



On Jul, 07, 2026

16 people who take Diflunisal and Ketoprofen together, and have interactions are studied.

Diflunisal and Ketoprofen drug interactions.

What are the common drug interactions of Diflunisal and Ketoprofen, by gender? *:

female:

  1. Anxiety
  2. Breath odour
  3. Drug hypersensitivity
  4. Emotional distress
  5. Feeding disorder (when children refuse to eat certain food groups)
  6. Migraine (headache)
  7. Osteoporosis (bones weak and more likely to break)
  8. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
  9. Urticaria (rash of round, red welts on the skin that itch intensely)
  10. Vision blurred

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Diflunisal and Ketoprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Osteoporosis (bones weak and more likely to break)
  5. Fracture
  6. Lower limb fracture
  7. Multiple fractures
  8. Nightmare (unpleasant dream)

40-49:

  1. Abdominal pain upper
  2. Feeding disorder (when children refuse to eat certain food groups)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Nausea (feeling of having an urge to vomit)
  5. Chronic gastritis (long lasting infection of stomach lining)
  6. Gastritis (inflammation of stomach)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Fall
  4. Femur fracture
  5. Gait disturbance
  6. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  7. Pain in extremity
  8. Renal tubular necrosis (death of kidney tubules)
  9. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

60+:

  1. Drug hypersensitivity

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 2 people, 12.50%
  2. Iron Deficiency: 2 people, 12.50%
  3. Benign Neoplasm Of Prostate (benign (non-cancerous) tumours of the prostate): 2 people, 12.50%
  4. Blood Testosterone Decreased: 2 people, 12.50%
  5. Diabetes: 2 people, 12.50%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  7. Hiv Infection: 2 people, 12.50%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 12.50%
  9. Magnesium Deficiency (lack of magnesium): 2 people, 12.50%
  10. Muscle Spasms (muscle contraction): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Diflunisal and Ketoprofen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diflunisal and Ketoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diflunisal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ketoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diflunisal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diflunisal and ketoprofen (the active ingredients of Diflunisal and Ketoprofen, respectively), and Diflunisal and Ketoprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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