Digoxin and Atovaquone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Atovaquone (atovaquone). Common drug interactions include thrombocytopenia among females and respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Atovaquone. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Atovaquone?

Atovaquone has active ingredients of atovaquone. eHealthMe is studying from 5,786 Atovaquone users. Check the latest studies of Atovaquone.

On Jul, 17, 2026

39 people who take Digoxin and Atovaquone together, and have interactions are studied.

Digoxin and Atovaquone drug interactions.

What are the common drug interactions of Digoxin and Atovaquone, by gender? *:

female:

Thrombocytopenia (decrease of platelets in blood)
Upper limb fracture
Emotional distress
Pain
Nausea (feeling of having an urge to vomit)
Chronic kidney disease
Fibula fracture
Lower limb fracture
Fatigue (feeling of tiredness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Respiratory failure (inadequate gas exchange by the respiratory system)
Fatigue (feeling of tiredness)
Abdominal pain
Abdominal pain upper
Abscess intestinal (collections of pus-intestinal)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Angiopathy (generic term for a disease of the blood vessels)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Asthenia (weakness)
Blood lactate dehydrogenase increased

What are the common drug interactions of Digoxin and Atovaquone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiac disorder
Fatigue (feeling of tiredness)
Swelling

20-29:

n/a

30-39:

n/a

40-49:

Lower limb fracture
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Multiple fractures
Osteoporosis (bones weak and more likely to break)
Pain
Spinal fracture (fracture in one of vertebrae)
Chronic kidney disease
Epistaxis (bleed from the nose)

50-59:

Fibula fracture
Ankle fracture
Bone density decreased
Chronic kidney disease
Death
Emotional distress
Pain
Renal failure (kidney dysfunction)
Tooth loss
Acute respiratory failure

60+:

Respiratory failure (inadequate gas exchange by the respiratory system)
Fatigue (feeling of tiredness)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Plasma cell myeloma (cancer that begins in plasma cells)
Blood bilirubin increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hepatic enzyme increased
Hepatotoxicity (chemical-driven liver damage)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Jaundice cholestatic

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 15.38%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 12.82%
Hiv Infection: 5 people, 12.82%
Nausea (feeling of having an urge to vomit): 3 people, 7.69%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.69%
Hypersensitivity: 3 people, 7.69%
High Blood Pressure: 3 people, 7.69%
Constipation: 3 people, 7.69%
Pain: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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