Digoxin and Maxipime drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Digoxin (digoxin) and Maxipime (cefepime hydrochloride). Common drug interactions include cardiac failure congestive among females and cough among males.
The phase IV clinical study analyzes what interactions people have when they take Digoxin and Maxipime. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
What is Maxipime?
Maxipime has active ingredients of cefepime hydrochloride. eHealthMe is studying from 4,279 Maxipime users. Check the latest studies of Maxipime.
51 people who take Digoxin and Maxipime together, and have interactions are studied.

What are the common drug interactions of Digoxin and Maxipime, by gender? *:
female:
- Cardiac failure congestive
- Decreased appetite
- Emotional distress
- Pain
- Atrioventricular block first degree (heart block first degree)
- Bronchial secretion retention
- Cardiac flutter (abnormal heart rhythm)
- Cardiomegaly (increased size of heart than normal)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Endocarditis bacterial (an inflammation of the inner layer of the heart by bacterial infection)
male:
- Cough
- Fall
- Urinary tract infection
- Pneumonia
- Chest injury
- Depressed level of consciousness
- Pyrexia (fever)
- Wheezing (a high-pitched whistling sound made while you breath)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Digoxin and Maxipime, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Death
10-19:
- Death
20-29:
n/a
30-39:
n/a
40-49:
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood lactate dehydrogenase increased
- Depressed level of consciousness
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hepatic enzyme increased
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Thrombocytopenia (decrease of platelets in blood)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Anaemia (lack of blood)
50-59:
- Renal injury (kidney injury)
- Stress
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Death
- Emotional distress
- Fear
- Injury
- Multi-organ failure (multisystem organ failure)
- Pain
60+:
- Pneumonia
- Pain
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
- Depression
- Fall
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Cardiac failure congestive
- Insomnia (sleeplessness)
What are the existing conditions these people have? *
- Cardiac Failure Chronic: 8 people, 15.69%
- Insomnia (sleeplessness): 7 people, 13.73%
- High Blood Pressure: 5 people, 9.80%
- Pneumonia: 4 people, 7.84%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 7.84%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 7.84%
- Stress And Anxiety: 3 people, 5.88%
- Nausea (feeling of having an urge to vomit): 3 people, 5.88%
- Gastric Cancer (stomach cancer): 3 people, 5.88%
- Cardiac Failure: 3 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Digoxin and Maxipime?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Digoxin and Maxipime:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Maxipime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxipime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and cefepime hydrochloride (the active ingredients of Digoxin and Maxipime, respectively), and Digoxin and Maxipime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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