Digoxin and Potassium citrate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Digoxin (digoxin) and Potassium citrate (potassium citrate). Common drug interactions include right ventricular failure among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Digoxin and Potassium citrate. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
What is Potassium citrate?
Potassium citrate has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 5,909 Potassium citrate users. Check the latest studies of Potassium citrate.
98 people who take Digoxin and Potassium citrate together, and have interactions are studied.

What are the common drug interactions of Digoxin and Potassium Citrate, by gender? *:
female:
- Right ventricular failure (right half of the heart fails to work)
- Vomiting
- Pneumonia
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiac failure
- Haematuria (presence of blood in urine)
- Haemoglobin decreased
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Visual disturbance
- Weight increased
male:
- Dyspnoea (difficult or laboured respiration)
- Pleural effusion (water on the lungs)
- Balance disorder
- Myalgia (muscle pain)
- Back pain
- Ejection fraction decreased (systolic heart failure)
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Vision blurred
- Constipation
What are the common drug interactions of Digoxin and Potassium Citrate, by age (0-1 to 60+)? *:
0-1:
- Abnormal faeces (abnormal stool)
- Agitation (state of anxiety or nervous excitement)
- Blood thyroid stimulating hormone increased
- Hyperthyroidism (over activity of the thyroid gland)
- Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
- Muscle rigidity (muscle stiffness)
- Slow response to stimuli (slow response by nerves)
2-9:
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Pulmonary congestion (congestion in the lungs)
- Subdural haematoma (blood collects between the skull and the surface of the brain)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
10-19:
- Operative haemorrhage (bleeding due to surgery)
20-29:
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
30-39:
n/a
40-49:
- Intestinal gangrene
- Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
50-59:
- Haematuria (presence of blood in urine)
60+:
- Dyspnoea (difficult or laboured respiration)
- Pleural effusion (water on the lungs)
- Pneumonia
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Asthenia (weakness)
- Circulatory collapse
- Septic shock (shock due to blood infection)
- Vomiting
- Congestive cardiomyopathy (weakening of heart muscle)
What are the existing conditions these people have? *
- High Blood Pressure: 17 people, 17.35%
- Cardiac Failure Chronic: 14 people, 14.29%
- Pain: 12 people, 12.24%
- Hypokalemia (low potassium): 11 people, 11.22%
- Cardiac Failure: 11 people, 11.22%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 10 people, 10.20%
- High Blood Cholesterol: 9 people, 9.18%
- Blood Potassium Decreased: 8 people, 8.16%
- Nausea (feeling of having an urge to vomit): 8 people, 8.16%
- Diabetes: 7 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Digoxin and Potassium citrate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Digoxin (93,740 reports)
- Potassium citrate (5,909 reports)
Browse all drug interactions of Digoxin and Potassium citrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Potassium citrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Potassium citrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and potassium citrate (the active ingredients of Digoxin and Potassium citrate, respectively), and Digoxin and Potassium citrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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