Digoxin and Sectral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Sectral (acebutolol hydrochloride). Common drug interactions include cervix disorder among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Sectral. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Sectral?

Sectral has active ingredients of acebutolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,548 Sectral users. Check the latest studies of Sectral.



On Jul, 09, 2026

67 people who take Digoxin and Sectral together, and have interactions are studied.

Digoxin and Sectral drug interactions.

What are the common drug interactions of Digoxin and Sectral, by gender? *:

female:

  1. Cervix disorder
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  4. Heparin-induced thrombocytopenia
  5. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Renal failure (kidney dysfunction)
  10. Renal infarct (kidney damage due to lack of blood supply)

male:

  1. Anaemia (lack of blood)
  2. Fatigue (feeling of tiredness)
  3. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  4. Lung infection
  5. Headache (pain in head)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Difficulty in walking
  8. Disease progression
  9. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  10. Heart rate increased

What are the common drug interactions of Digoxin and Sectral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Psoriasis (immune-mediated disease that affects the skin)
  2. Purpura (purplish discoloration of the skin)
  3. Disease recurrence
  4. Dry eye (lack of adequate tears)
  5. Keratoconjunctivitis sicca (inflammation of the conjunctiva and cornea of the eye with decreased tears)

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardiac arrest
  2. Cardiac pacemaker malfunction
  3. Hypotension (abnormally low blood pressure)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Renal failure (kidney dysfunction)
  6. Suicide attempt
  7. White blood cell count decreased

50-59:

  1. Bladder discomfort
  2. Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)
  3. Bloody discharge
  4. Breast pain
  5. Cardiac valve disease (heart valve disease)
  6. Cardioactive drug level below therapeutic
  7. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  8. Cervicobrachial syndrome (pain in neck and arm with changing location)
  9. Chest pain
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

60+:

  1. Anaemia (lack of blood)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Toxicoderma (a disease of the skin caused by a toxic agent)
  4. Blood creatinine increased
  5. Cervix disorder
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  9. Fall
  10. Heparin-induced thrombocytopenia

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 6 people, 8.96%

* Approximation only. Some reports may have incomplete information.

Do you take Digoxin and Sectral?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Digoxin and Sectral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sectral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Digoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sectral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on digoxin and acebutolol hydrochloride (the active ingredients of Digoxin and Sectral, respectively), and Digoxin and Sectral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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