Digoxin and Simbrinza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Simbrinza (brimonidine tartrate; brinzolamide). Common drug interactions include dizziness among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Simbrinza. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Simbrinza?

Simbrinza has active ingredients of brimonidine tartrate; brinzolamide. It is often used in glaucoma. eHealthMe is studying from 4,543 Simbrinza users. Check the latest studies of Simbrinza.

On Jul, 19, 2026

16 people who take Digoxin and Simbrinza together, and have interactions are studied.

Digoxin and Simbrinza drug interactions.

What are the common drug interactions of Digoxin and Simbrinza, by gender? *:

female:

Dizziness
Fluid retention (an abnormal accumulation of fluid in the blood)
Insomnia (sleeplessness)
Pneumonia
Blood potassium decreased
Blood pressure fluctuation
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

male:

Pleural effusion (water on the lungs)
Acute respiratory failure
Cough
Death
Diarrhoea
Dizziness
Drug ineffective
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Digoxin and Simbrinza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dizziness
Death
Blood pressure fluctuation
Cardiac arrest
Cardiac failure
Carotid artery stenosis (narrowing of carotid artery)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 12.50%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 12.50%
Iron Deficiency Anaemia: 2 people, 12.50%
Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 2 people, 12.50%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 6.25%
Prostate Cancer: 1 person, 6.25%
Pain: 1 person, 6.25%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 6.25%
Metastases To Lung (cancer spreads to lung): 1 person, 6.25%
Dry Eyes (lack of adequate tears): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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