Digoxin and Xywav drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Xywav (calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate). Common drug interactions include cataract among females and rib fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Xywav. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Xywav?

Xywav has active ingredients of calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate. eHealthMe is studying from 7,134 Xywav users. Check the latest studies of Xywav.

On Jul, 06, 2026

11 people who take Digoxin and Xywav together, and have interactions are studied.

What are the common drug interactions of Digoxin and Xywav, by gender? *:

female:

Cataract (clouding of the lens inside the eye)
Dry eye (lack of adequate tears)
Eye infection
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nightmare (unpleasant dream)
Suicidal ideation
Suicide attempt

male:

Rib fracture
Foot fracture
Tremor (trembling or shaking movements in one or more parts of your body)
Type 2 diabetes mellitus
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Hunger
Lower limb fracture
Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Digoxin and Xywav, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Eye infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nightmare (unpleasant dream)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 100.00%
Drowsiness: 11 people, 100.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 90.91%
Oedema (fluid collection in tissue): 1 person, 9.09%
Neuropathy Peripheral (surface nerve damage): 1 person, 9.09%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%
Heart Attack: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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