Dilantin and Aromasin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dilantin (phenytoin sodium) and Aromasin (exemestane). Common drug interactions include nausea among females and adenocarcinoma among males.
The phase IV clinical study analyzes what interactions people have when they take Dilantin and Aromasin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Dilantin?
Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.
What is Aromasin?
Aromasin has active ingredients of exemestane. It is often used in breast cancer. eHealthMe is studying from 12,863 Aromasin users. Check the latest studies of Aromasin.
11 people who take Dilantin and Aromasin together, and have interactions are studied.

What are the common drug interactions of Dilantin and Aromasin, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
- Adenoma benign (non-cancerous tumour -secreting)
- Adnexa uteri cyst (ovarian cysts)
- Allergic sinusitis
- Anxiety
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Aortic valve sclerosis (narrowing of the aortic valve)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthenia (weakness)
male:
- Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
- Adenoma benign (non-cancerous tumour -secreting)
- Asthenia (weakness)
- Asthma
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
- Breast cyst
- Breast mass
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
What are the common drug interactions of Dilantin and Aromasin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
- Adenoma benign (non-cancerous tumour -secreting)
- Adnexa uteri cyst (ovarian cysts)
- Allergic sinusitis
- Anxiety
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Aortic calcification (aortic calcification sign of heart valve disease)
- Aortic valve sclerosis (narrowing of the aortic valve)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
30-39:
n/a
40-49:
- Confusional state
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Headache (pain in head)
- Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
- Nausea (feeling of having an urge to vomit)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Pain in extremity
- Unresponsive to stimuli
- Vomiting
- Apnoeic attack
50-59:
- Breast haemorrhage (bleeding in breast)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
60+:
- Injury
- Arthralgia (joint pain)
- Asthenia (weakness)
- Asthma
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
- Breast cyst
- Breast mass
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
What are the existing conditions these people have? *
- Stress And Anxiety: 4 people, 36.36%
- Metastases To Bone (cancer spreads to bone): 3 people, 27.27%
- Breast Cancer Metastatic: 2 people, 18.18%
- Joint Pain: 1 person, 9.09%
- Depression: 1 person, 9.09%
- Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 9.09%
- Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 9.09%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 9.09%
- Inflammation: 1 person, 9.09%
- Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Dilantin and Aromasin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dilantin and Aromasin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dilantin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aromasin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dilantin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aromasin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
- Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on phenytoin sodium and exemestane (the active ingredients of Dilantin and Aromasin, respectively), and Dilantin and Aromasin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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