Prelone and Omeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prelone (prednisolone) and Omeprazole (omeprazole). Common drug interactions include intervertebral disc protrusion among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Prelone and Omeprazole. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Prelone?

Prelone has active ingredients of prednisolone. It is often used in asthma. eHealthMe is studying from 869 Prelone users. Check the latest studies of Prelone.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.



On Jul, 29, 2026

83 people who take Prelone and Omeprazole together, and have interactions are studied.

Prelone and Omeprazole drug interactions.

What are the common drug interactions of Prelone and Omeprazole, by gender? *:

female:

  1. Intervertebral disc protrusion (spinal disc protrusion)
  2. Cardiac arrest
  3. Haemoglobin decreased
  4. Hip fracture
  5. Patient-device incompatibility
  6. Urinary tract infection
  7. Pain in extremity
  8. Procedural pain
  9. Weight increased
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

male:

  1. Pain
  2. Urinary tract infection
  3. Infection
  4. Kidney infection
  5. Nausea (feeling of having an urge to vomit)
  6. Nervous system neoplasm (a tumour affecting the nervous system)
  7. Peripheral nerve lesion
  8. Peroneal nerve palsy
  9. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  10. Therapeutic response decreased (less preventive response)

What are the common drug interactions of Prelone and Omeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Respiratory syncytial virus bronchiolitis (a lower respiratory tract infection due to virus)
  2. Back disorder
  3. Body temperature increased
  4. Diarrhoea
  5. Femur fracture
  6. Fluid retention (an abnormal accumulation of fluid in the blood)
  7. Increased upper airway secretion
  8. Irritability
  9. Platelet count decreased
  10. Pneumonia

10-19:

  1. Conjunctivitis (pink eye)
  2. Disease progression
  3. Dizziness
  4. Ill-defined disorder
  5. Infection
  6. Kidney infection
  7. Nausea (feeling of having an urge to vomit)
  8. Nervous system neoplasm (a tumour affecting the nervous system)
  9. Peripheral nerve lesion
  10. Peroneal nerve palsy

20-29:

  1. Nausea (feeling of having an urge to vomit)
  2. Anaemia (lack of blood)
  3. Dizziness
  4. Kidney infection
  5. Therapeutic response decreased (less preventive response)
  6. Urinary tract infection
  7. Arthralgia (joint pain)
  8. Bone marrow failure
  9. Conjunctivitis (pink eye)
  10. Fall

30-39:

  1. Abdominal distension
  2. Constipation
  3. Hepatitis (inflammation of the liver)
  4. Hypersensitivity
  5. Immunodeficiency
  6. Pain

40-49:

  1. Intervertebral disc protrusion (spinal disc protrusion)
  2. Pain
  3. Swelling
  4. Weight increased
  5. Dyspnoea (difficult or laboured respiration)
  6. Hypertension (high blood pressure)
  7. Pneumonia
  8. Spinal disorder (disease of spine a back bone)

50-59:

  1. Chest discomfort
  2. Dyspnoea (difficult or laboured respiration)
  3. Fatigue (feeling of tiredness)
  4. Lipids increased (excess lipid in body)
  5. Oedema (fluid collection in tissue)
  6. Rheumatoid factor increased
  7. Sensation of heaviness
  8. Swelling
  9. Weight decreased
  10. Wound

60+:

  1. Gait disturbance
  2. Depression
  3. Fatigue (feeling of tiredness)
  4. Muscle rigidity (muscle stiffness)
  5. Post procedural complication
  6. Procedural pain
  7. Pain
  8. Pyrexia (fever)
  9. Dyspnoea (difficult or laboured respiration)
  10. Cough

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 55 people, 66.27%
  2. Gastric Disorder (disease of stomach): 30 people, 36.14%
  3. High Blood Pressure: 17 people, 20.48%
  4. Osteoporosis (bones weak and more likely to break): 14 people, 16.87%
  5. Bone Disorder: 13 people, 15.66%
  6. Pain: 12 people, 14.46%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 14.46%
  8. Stress And Anxiety: 11 people, 13.25%
  9. Depression: 10 people, 12.05%
  10. High Blood Cholesterol: 8 people, 9.64%

* Approximation only. Some reports may have incomplete information.

Do you take Prelone and Omeprazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prelone and Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prelone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prelone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on prednisolone and omeprazole (the active ingredients of Prelone and Omeprazole, respectively), and Prelone and Omeprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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