Dilantin and Omnicef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilantin (phenytoin sodium) and Omnicef (cefdinir). Common drug interactions include depression among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Dilantin and Omnicef. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

On Jul, 04, 2026

14 people who take Dilantin and Omnicef together, and have interactions are studied.

What are the common drug interactions of Dilantin and Omnicef, by gender? *:

female:

Depression
Drug abuse
Drug abuser
Drug hypersensitivity
Drug screen positive
Dry mouth
Epistaxis (bleed from the nose)
Fall
Flatulence (flatus expelled through the anus)
Gastritis (inflammation of stomach)

male:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Nausea (feeling of having an urge to vomit)
Renal failure chronic (long lasting kidney dysfunction)
Weight decreased
Anaemia (lack of blood)
Anaemia of chronic disease
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Hypertensive heart disease
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)

What are the common drug interactions of Dilantin and Omnicef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug toxicity
Gait disturbance
Joint stiffness
Prostatitis (inflammation of the prostate gland)
Therapeutic response decreased (less preventive response)

20-29:

n/a

30-39:

Drug abuse
Drug abuser
Drug screen positive
Fall
Flatulence (flatus expelled through the anus)
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haematemesis (vomiting of blood)

40-49:

Back pain
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

50-59:

Acute respiratory failure
Oedema peripheral (superficial swelling)
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Renal failure chronic (long lasting kidney dysfunction)
Weight decreased
Anaemia (lack of blood)
Anaemia of chronic disease
Blood pressure increased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)

60+:

Drug hypersensitivity

What are the existing conditions these people have? *

Pain: 3 people, 21.43%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 21.43%
Sleep Disorder: 2 people, 14.29%
Depression: 2 people, 14.29%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 1 person, 7.14%
Reduction Of Increased Intracranial Pressure (reducing intracranial pressure): 1 person, 7.14%
Menopausal Symptoms: 1 person, 7.14%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.14%
Csf Volume Increased: 1 person, 7.14%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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