Dilaudid and Bortezomib drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilaudid (hydromorphone hydrochloride) and Bortezomib (bortezomib). Common drug interactions include febrile neutropenia among females and infection among males.

The phase IV clinical study analyzes what interactions people have when they take Dilaudid and Bortezomib. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Bortezomib?

Bortezomib has active ingredients of bortezomib. eHealthMe is studying from 30,912 Bortezomib users. Check the latest studies of Bortezomib.



On Jul, 16, 2026

73 people who take Dilaudid and Bortezomib together, and have interactions are studied.

Dilaudid and Bortezomib drug interactions.

What are the common drug interactions of Dilaudid and Bortezomib, by gender? *:

female:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Plasma cell myeloma (cancer that begins in plasma cells)
  3. Pneumonia
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Osteomyelitis (infection of bone)
  8. Platelet count decreased
  9. Pyelonephritis (inflammation of kidney caused by bacteria)
  10. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

male:

  1. Infection
  2. Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
  3. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  4. Amyloidosis (a tumour within which amyloid is produced)
  5. Anaemia (lack of blood)
  6. Arthralgia (joint pain)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Cataract (clouding of the lens inside the eye)
  10. Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)

What are the common drug interactions of Dilaudid and Bortezomib, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Apnoea (suspension of external breathing)
  2. Blood culture positive
  3. Citrobacter test positive
  4. Hypotension (abnormally low blood pressure)
  5. Hypoxia (low oxygen in tissues)
  6. Klebsiella test positive
  7. Pyrexia (fever)
  8. Unresponsive to stimuli
  9. Vomiting

40-49:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Alopecia (absence of hair from areas of the body)
  3. Anaemia (lack of blood)
  4. Blood creatinine increased
  5. Cellulitis (infection under the skin)
  6. Chills (felling of cold)
  7. Cough
  8. Decreased appetite
  9. Device related infection
  10. Fatigue (feeling of tiredness)

50-59:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Osteonecrosis (death of bone)
  3. Pneumonia
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Chills (felling of cold)
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Muscle haemorrhage (bleeding in muscle)
  8. Pyelonephritis (inflammation of kidney caused by bacteria)
  9. Pyrexia (fever)
  10. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

60+:

  1. Pneumonia
  2. Cystitis (inflammation of the wall of the bladder)
  3. Neuropathy peripheral (surface nerve damage)
  4. Abdominal pain
  5. Bone marrow failure
  6. Drug ineffective
  7. Intestinal obstruction
  8. Metastatic malignant melanoma (spreadable cancer tumour of melanine)
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Thrombosis (formation of a blood clot inside a blood vessel)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 48 people, 65.75%
  2. Respiratory Distress (difficulty in breathing): 6 people, 8.22%
  3. Faeces Hard: 6 people, 8.22%
  4. Dental Caries: 6 people, 8.22%
  5. Asthma: 6 people, 8.22%
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 8.22%
  7. Constipation: 5 people, 6.85%
  8. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 4 people, 5.48%
  9. Neuropathy Peripheral (surface nerve damage): 4 people, 5.48%
  10. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dilaudid and Bortezomib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bortezomib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dilaudid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bortezomib and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride and bortezomib (the active ingredients of Dilaudid and Bortezomib, respectively), and Dilaudid and Bortezomib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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