Dilaudid and Tradjenta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dilaudid (hydromorphone hydrochloride) and Tradjenta (linagliptin). Common drug interactions include chronic kidney disease among females and cellulitis among males.
The phase IV clinical study analyzes what interactions people have when they take Dilaudid and Tradjenta. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Dilaudid?
Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.
What is Tradjenta?
Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.
23 people who take Dilaudid and Tradjenta together, and have interactions are studied.

What are the common drug interactions of Dilaudid and Tradjenta, by gender? *:
female:
- Chronic kidney disease
- Epistaxis (bleed from the nose)
- Nausea (feeling of having an urge to vomit)
- Paranasal cyst (cyst near the nose)
- Breast cancer
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Death
- Disability
male:
- Cellulitis (infection under the skin)
- Gas gangrene (bacterial infection that produces gas within tissues)
- Death
- Renal failure (kidney dysfunction)
- Tooth abscess (pus formation in tooth)
- Abdominal discomfort
- Arthralgia (joint pain)
- Blood glucose increased
- Diarrhoea
- Disease progression
What are the common drug interactions of Dilaudid and Tradjenta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Epistaxis (bleed from the nose)
- Nausea (feeling of having an urge to vomit)
- Paranasal cyst (cyst near the nose)
- Arthralgia (joint pain)
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Death
- Disturbance in attention
- Gas gangrene (bacterial infection that produces gas within tissues)
- Groin abscess (pus in groin)
50-59:
- Cellulitis (infection under the skin)
- Gas gangrene (bacterial infection that produces gas within tissues)
- Groin abscess (pus in groin)
- Groin pain
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Scrotal cyst (cyst of scrotum)
- Scrotal pain
- Scrotal swelling
- Testicular pain (pain in testes)
- Chronic kidney disease
60+:
- Death
- Breast cancer
- Hepatotoxicity (chemical-driven liver damage)
- Intraductal papillary mucinous neoplasm (tumour (neoplasm) that grows within the pancreatic ducts)
- Oesophageal haemorrhage (bleeding from oesophagus)
- Pleural effusion (water on the lungs)
- Rash
- Renal cancer (cancer of kidney)
- Renal failure acute (rapid kidney dysfunction)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
What are the existing conditions these people have? *
- High Blood Pressure: 10 people, 43.48%
- Stress And Anxiety: 6 people, 26.09%
- High Blood Cholesterol: 6 people, 26.09%
- Cardiac Disorder: 4 people, 17.39%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 17.39%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 17.39%
- Type 2 Diabetes: 4 people, 17.39%
- Hypotension (abnormally low blood pressure): 3 people, 13.04%
- Constipation: 3 people, 13.04%
- Weight Decreased: 3 people, 13.04%
* Approximation only. Some reports may have incomplete information.
Do you take Dilaudid and Tradjenta?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dilaudid and Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dilaudid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dilaudid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tradjenta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydromorphone hydrochloride and linagliptin (the active ingredients of Dilaudid and Tradjenta, respectively), and Dilaudid and Tradjenta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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