Dilaudid and Votrient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilaudid (hydromorphone hydrochloride) and Votrient (pazopanib hydrochloride). Common drug interactions include hair colour changes among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Dilaudid and Votrient. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.

On Jul, 14, 2026

79 people who take Dilaudid and Votrient together, and have interactions are studied.

Dilaudid and Votrient drug interactions.

What are the common drug interactions of Dilaudid and Votrient, by gender? *:

female:

Hair colour changes
Diarrhoea
Hypersomnia (excessive daytime sleepiness (eds))
Hospitalisation
Abdominal pain
Alopecia (absence of hair from areas of the body)
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Dyspepsia (indigestion)
Hypophagia (reduced food intake)

male:

Diarrhoea
Death
Hand-foot-and-mouth disease
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lip ulceration (ulcer of lip)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Neuropathy peripheral (surface nerve damage)
Restrictive pulmonary disease (reduction in total lung capacity)
Skin discolouration (change of skin colour)
Thymic cancer metastatic

What are the common drug interactions of Dilaudid and Votrient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hair colour changes
Nail discolouration (change in nail colour)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Aortic valve incompetence
Blood pressure increased
Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
Cardiac failure
Chest pain

30-39:

Death
Burns third degree
Gastric neoplasm (a tumour that develops in the stomach)
Hypoaesthesia (reduced sense of touch or sensation)
Inguinal mass
Malignant neoplasm progression (cancer tumour came back)
Pyrexia (fever)
Rash
Tumour pain
Wound

40-49:

Arthralgia (joint pain)
Cough
Death
Decreased appetite
Diarrhoea
Disease progression
Disturbance in attention
Haemorrhage (bleeding)
Intervertebral disc protrusion (spinal disc protrusion)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

50-59:

Nausea (feeling of having an urge to vomit)
Vomiting
Confusional state
Fatigue (feeling of tiredness)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Haemorrhage (bleeding)
Abdominal discomfort
Abdominal distension
Abdominal pain
Anaemia (lack of blood)

60+:

Alanine aminotransferase increased
Amylase increased
Decreased appetite
Malignant neoplasm progression (cancer tumour came back)
Hospitalisation
Abdominal pain upper
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Aura
Blood potassium increased

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 35 people, 44.30%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 6 people, 7.59%

* Approximation only. Some reports may have incomplete information.

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