Dimenhydrinate and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dimenhydrinate (dimenhydrinate) and Colace (docusate ). Common drug interactions include haemoglobin decreased among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Dimenhydrinate and Colace. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Dimenhydrinate?

Dimenhydrinate has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 6,644 Dimenhydrinate users. Check the latest studies of Dimenhydrinate.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

57 people who take Dimenhydrinate and Colace together, and have interactions are studied.

Dimenhydrinate and Colace drug interactions.

What are the common drug interactions of Dimenhydrinate and Colace, by gender? *:

female:

Haemoglobin decreased
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Heart rate increased
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Irritability
Kidney transplant rejection
Leukopenia (less number of white blood cells in blood)
Lymphocele (a collection of lymphatic fluid within the body not bordered by epithelial lining)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

male:

Haemoglobin decreased
Anaphylactic reaction (serious allergic reaction)
Haematocrit decreased
Haemorrhage intracranial (bleeding within the skull)
Intestinal obstruction
Leukaemia (blood or bone marrow cancer)
Osteomyelitis (infection of bone)
Pyrexia (fever)
Rash
Red blood cell count decreased

What are the common drug interactions of Dimenhydrinate and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Haemorrhage (bleeding)
Acute leukaemia (blood cancer)
Drug ineffective

20-29:

Flushing (the warm, red condition of human skin)
Infusion related reaction
Pruritus (severe itching of the skin)
Weight increased
Abdominal pain
Altered state of consciousness (altered state of mind)
Drug abuse
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Furuncle (infection of the hair follicle)

30-39:

Contusion (a type of hematoma of tissue in which capillaries)
Cough
Cushingoid (obesity and weakening of the muscles)
Cytomegalovirus test positive
Decreased appetite
Depressed mood
Diphtheria (upper respiratory tract illness caused by corynebacterium diphtheriae)
Discomfort
Dizziness
Dyspnoea (difficult or laboured respiration)

40-49:

Fatigue (feeling of tiredness)
Infusion related reaction
Insomnia (sleeplessness)
Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system)
Headache (pain in head)

50-59:

Anaphylactic reaction (serious allergic reaction)
Rash
Abscess (pus)
Acanthosis (thickening of the skin)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Asthma
Cardiac failure congestive
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Confusional state

60+:

Pelvic fracture
Arthralgia (joint pain)
Haemoglobin decreased
Haemorrhage intracranial (bleeding within the skull)
Intestinal obstruction
Leukaemia (blood or bone marrow cancer)
Osteomyelitis (infection of bone)
Pyrexia (fever)
Red blood cell count decreased
General physical health deterioration (weak health status)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 28.07%
Pain: 8 people, 14.04%
Multiple Myeloma (cancer of the plasma cells): 7 people, 12.28%
High Blood Pressure: 7 people, 12.28%
Stress And Anxiety: 6 people, 10.53%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 8.77%
Hypokalemia (low potassium): 5 people, 8.77%
Ankylosing Spondylitis (type of arthritis affecting the spine): 5 people, 8.77%
High Blood Cholesterol: 5 people, 8.77%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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