Diovan and Indocin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Diovan (valsartan) and Indocin (indomethacin). Common drug interactions include stress among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Diovan and Indocin. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.
What is Diovan?
Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.
What is Indocin?
Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.
74 people who take Diovan and Indocin together, and have interactions are studied.

What are the common drug interactions of Diovan and Indocin, by gender? *:
female:
- Stress
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Blood urea increased
- Dysuria (painful or difficult urination)
- Fall
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Weight increased
- Dyspnoea (difficult or laboured respiration)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Renal failure (kidney dysfunction)
male:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Depression
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gouty arthritis (joint inflammation with crystal formation)
- Influenza
- Limb injury
- Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
What are the common drug interactions of Diovan and Indocin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Blood cholesterol increased
- Blood creatine phosphokinase increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Depression
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
40-49:
- Arthralgia (joint pain)
- Cellulitis (infection under the skin)
- Forced expiratory volume decreased (decreased lung expired air volume)
- Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
- Pancreatitis (inflammation of pancreas)
- Renal disorder (kidney disease)
50-59:
- Drug hypersensitivity
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Oliguria (not enough urine)
- Abdominal discomfort
- Anxiety
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Atrioventricular block first degree (heart block first degree)
60+:
- Decreased appetite
- Anxiety
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Anaemia (lack of blood)
- Fall
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haemoglobin decreased
- Leukaemia granulocytic (a malignant neoplasm of blood-forming tissues)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Weakness
What are the existing conditions these people have? *
- High Blood Cholesterol: 11 people, 14.86%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 14.86%
- Cardiac Disorder: 8 people, 10.81%
- Pain: 7 people, 9.46%
- Diabetes: 5 people, 6.76%
* Approximation only. Some reports may have incomplete information.
Do you take Diovan and Indocin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Diovan and Indocin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Diovan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Indocin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diovan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Indocin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
- Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on valsartan and indomethacin (the active ingredients of Diovan and Indocin, respectively), and Diovan and Indocin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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