Diovan and Symmetrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diovan (valsartan) and Symmetrel (amantadine hydrochloride). Common drug interactions include palpitations among females and blood pressure decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Diovan and Symmetrel. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.

What is Symmetrel?

Symmetrel has active ingredients of amantadine hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,398 Symmetrel users. Check the latest studies of Symmetrel.

On Jul, 11, 2026

86 people who take Diovan and Symmetrel together, and have interactions are studied.

What are the common drug interactions of Diovan and Symmetrel, by gender? *:

female:

Palpitations (feelings or sensations that your heart is pounding or racing)
Vomiting
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Pneumonia
Anxiety disorder
Arthralgia (joint pain)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypokinesia (decreased bodily movement)
Loss of consciousness
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

male:

Blood pressure decreased
Alanine aminotransferase increased
Oedema (fluid collection in tissue)
White blood cell count decreased
Dementia (madness)
Depressed level of consciousness
Dysphagia (a condition in which swallowing is difficult or painful)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Interstitial lung disease
Oxygen saturation decreased

What are the common drug interactions of Diovan and Symmetrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug level increased
Dysphagia (a condition in which swallowing is difficult or painful)
Fall
Hypoglycaemia (deficiency of glucose in the bloodstream)
Immobile (not moving)
Mitral valve incompetence (inefficient heart valve)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Tremor (trembling or shaking movements in one or more parts of your body)
Blood pressure decreased
Abdominal discomfort
Arthralgia (joint pain)
Chest discomfort
Decreased appetite
Diarrhoea
Discomfort
Electrolyte imbalance
Gastroenteritis (inflammation of stomach and intestine)

What are the existing conditions these people have? *

Cerebral Infarction (less blood supply to brain resulting tissue damage): 14 people, 16.28%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 13.95%
Nausea (feeling of having an urge to vomit): 8 people, 9.30%
Gastritis (inflammation of stomach): 7 people, 8.14%
Insomnia (sleeplessness): 6 people, 6.98%
Dementia (madness): 6 people, 6.98%
Urinary Tract Infection: 5 people, 5.81%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 5.81%
Dizziness: 5 people, 5.81%
Depression: 5 people, 5.81%

* Approximation only. Some reports may have incomplete information.

Do you take Diovan and Symmetrel?

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