Imuran and Desyrel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Imuran (azathioprine) and Desyrel (trazodone hydrochloride). Common drug interactions include anxiety among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Imuran and Desyrel. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.
What is Imuran?
Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.
What is Desyrel?
Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.
27 people who take Imuran and Desyrel together, and have interactions are studied.

What are the common drug interactions of Imuran and Desyrel, by gender? *:
female:
- Anxiety
- Arthralgia (joint pain)
- Asthenia (weakness)
- Hypoaesthesia (reduced sense of touch or sensation)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arrhythmia (irregular heartbeat)
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Headache (pain in head)
male:
- Abdominal pain
- Anxiety
- Back pain
- Cough
- Dyspnoea (difficult or laboured respiration)
- Ejaculation failure
- Hepatitis (inflammation of the liver)
- Large intestine perforation (hole in large intestine)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Spinal fracture (fracture in one of vertebrae)
What are the common drug interactions of Imuran and Desyrel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Dizziness
- Emotional distress
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
40-49:
- Cough
- Hepatitis (inflammation of the liver)
50-59:
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
- Constipation
- Dyspepsia (indigestion)
- Blood triglycerides increased
- Cough
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic complication
- Dyspnoea (difficult or laboured respiration)
- Femur fracture
60+:
- Abdominal hernia
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Blood amylase increased
- Diarrhoea
- Ejaculation failure
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Unevaluable reaction
- Pulmonary embolism (blockage of the main artery of the lung)
- Small intestinal obstruction (blockage in small intestine)
What are the existing conditions these people have? *
- Pain: 8 people, 29.63%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 22.22%
- Depression: 6 people, 22.22%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.81%
- Seasonal Allergy (allergic condition due to certain season): 4 people, 14.81%
- Nausea And Vomiting: 4 people, 14.81%
- Nausea (feeling of having an urge to vomit): 4 people, 14.81%
- Iron Deficiency Anaemia: 4 people, 14.81%
- Stress And Anxiety: 4 people, 14.81%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 14.81%
* Approximation only. Some reports may have incomplete information.
Do you take Imuran and Desyrel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Imuran and Desyrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Imuran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Desyrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Imuran and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Desyrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .
- Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on azathioprine and trazodone hydrochloride (the active ingredients of Imuran and Desyrel, respectively), and Imuran and Desyrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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