Diphen and Tazverik drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diphen (diphenhydramine hydrochloride) and Tazverik (tazemetostat hydrobromide). Common drug interactions include diarrhoea among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Diphen and Tazverik. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.

What is Tazverik?

Tazverik has active ingredients of tazemetostat hydrobromide. eHealthMe is studying from 1,248 Tazverik users. Check the latest studies of Tazverik.



On Jul, 07, 2026

38 people who take Diphen and Tazverik together, and have interactions are studied.

Diphen and Tazverik drug interactions.

What are the common drug interactions of Diphen and Tazverik, by gender? *:

female:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Pneumonia
  4. Pyrexia (fever)
  5. Urinary tract infection
  6. Asthenia (weakness)
  7. Beta 2 microglobulin increased
  8. Disease progression
  9. Dysuria (painful or difficult urination)
  10. Fatigue (feeling of tiredness)

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Pneumonia
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Disease progression
  8. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  9. Hospitalisation
  10. Pain

What are the common drug interactions of Diphen and Tazverik, by age (0-1 to 60+)? *:

0-1:

  1. Death
  2. Hospitalisation
  3. Pyrexia (fever)
  4. Vomiting

2-9:

  1. Abdominal pain upper

10-19:

  1. Death
  2. Nausea (feeling of having an urge to vomit)

20-29:

n/a

30-39:

  1. Pneumonia

40-49:

n/a

50-59:

n/a

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Chest pain
  4. Epistaxis (bleed from the nose)
  5. Haematochezia (passage of stools containing blood)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Arthralgia (joint pain)
  8. Beta 2 microglobulin increased
  9. Disease progression
  10. Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 7.89%
  2. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 2 people, 5.26%
  3. Epithelioid Sarcoma (cancer of fingers, hands, and forearms): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Diphen and Tazverik?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diphen and Tazverik:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tazverik:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diphen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tazverik and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and tazemetostat hydrobromide (the active ingredients of Diphen and Tazverik, respectively), and Diphen and Tazverik (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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