Diphenhydramine hydrochloride and Ciclopirox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diphenhydramine hydrochloride (diphenhydramine hydrochloride) and Ciclopirox (ciclopirox). Common drug interactions include chronic obstructive pulmonary disease among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Diphenhydramine hydrochloride and Ciclopirox. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Diphenhydramine hydrochloride?

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 26,097 Diphenhydramine hydrochloride users. Check the latest studies of Diphenhydramine hydrochloride.

What is Ciclopirox?

Ciclopirox has active ingredients of ciclopirox. eHealthMe is studying from 2,646 Ciclopirox users. Check the latest studies of Ciclopirox.

On Jul, 26, 2026

22 people who take Diphenhydramine hydrochloride and Ciclopirox together, and have interactions are studied.

Diphenhydramine hydrochloride and Ciclopirox drug interactions.

What are the common drug interactions of Diphenhydramine Hydrochloride and Ciclopirox, by gender? *:

female:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Connective tissue disorder (any disease that has the connective tissues of the body)
Constipation
Cough
Depression
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gingival bleeding (bleeding gums)

male:

Emotional distress
Anxiety
Cellulitis (infection under the skin)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
Gangrene (body tissue dies)
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Leukocytosis (increased white blood cells)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

What are the common drug interactions of Diphenhydramine Hydrochloride and Ciclopirox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arthralgia (joint pain)
Diarrhoea
Fall
Fatigue (feeling of tiredness)
Hepatic enzyme increased
Hepatomegaly (abnormal enlargement of the liver)
Ligament sprain (ligament stretched)
Nausea (feeling of having an urge to vomit)
Pain
Respiratory tract infection

20-29:

n/a

30-39:

n/a

40-49:

Emotional distress
Fatigue (feeling of tiredness)
Pain
Anxiety
Chronic kidney disease
Dizziness
Nephrolithiasis (calculi in the kidneys)
Renal impairment (severely reduced kidney function)
Abscess limb (limb infection)
Anal abscess

50-59:

Nausea (feeling of having an urge to vomit)
Neck pain
Nerve injury
Onychoclasis (breaking of the nails)
Oropharyngeal pain
Pain
Pain in extremity
Peripheral swelling
Poor venous access
Procedural complication

60+:

Limb injury
Abdominal distension
Chest pain
Chills (felling of cold)
Contusion (a type of hematoma of tissue in which capillaries)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Dizziness
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 5 people, 22.73%
Immune System Disorder: 5 people, 22.73%
Hereditary Angioedema (recurrent episodes of severe swelling): 5 people, 22.73%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Hiv Infection: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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