Diprivan and Sertraline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprivan (propofol) and Sertraline (sertraline hydrochloride). Common drug interactions include weight decreased among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Diprivan and Sertraline. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.



On Jul, 11, 2026

12 people who take Diprivan and Sertraline together, and have interactions are studied.

Diprivan and Sertraline drug interactions.

What are the common drug interactions of Diprivan and Sertraline, by gender? *:

female:

  1. Weight decreased
  2. Abdominal pain upper
  3. Anti-hbc antibody positive
  4. Epstein-barr virus antibody positive
  5. Hepatitis (inflammation of the liver)
  6. Rigors (an episode of shaking or exaggerated shivering)
  7. Blood amylase increased
  8. Lipase increased
  9. Pulmonary vascular disorder
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nodal rhythm (40-50 beats per minute)
  4. Renal hypertension (high blood pressure caused by the kidneys hormonal response)
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Atrioventricular block (heart block)

What are the common drug interactions of Diprivan and Sertraline, by age (0-1 to 60+)? *:

0-1:

  1. Foetal arrhythmia (abnormal rate or rhythm of the foetus heartbeat)
  2. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  3. Hepatocellular injury (liver injury)
  4. Hypotonia neonatal (low muscle tone in neonatal)
  5. Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
  6. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  7. Weight decreased

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Hepatitis (inflammation of the liver)
  2. Rigors (an episode of shaking or exaggerated shivering)
  3. Weight decreased
  4. Abdominal pain upper
  5. Blood amylase increased
  6. Lipase increased
  7. General physical condition
  8. General physical health deterioration (weak health status)
  9. Pancreatic enzymes increased
  10. Anti-hbc antibody positive

40-49:

  1. Atrioventricular block (heart block)
  2. Bradycardia (abnormally slow heart action)
  3. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  4. Nodal rhythm (40-50 beats per minute)
  5. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal tubular necrosis (death of kidney tubules)
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  7. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  8. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Abdominal pain upper
  3. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  4. Atrioventricular block complete (heart block complete)
  5. Back pain
  6. Bacteraemia (presence of bacteria in the blood)
  7. Blood pressure decreased
  8. Body temperature decreased
  9. Bone disorder
  10. Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 33.33%
  2. Pain: 3 people, 25.00%
  3. Constipation: 2 people, 16.67%
  4. High Blood Pressure: 2 people, 16.67%
  5. Stupor (lack of critical cognitive function and level of consciousness): 1 person, 8.33%
  6. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 8.33%
  7. Bipolar Disorder (mood disorder): 1 person, 8.33%
  8. Cardiac Disorder: 1 person, 8.33%
  9. Cardiac Failure Congestive: 1 person, 8.33%
  10. Chest Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diprivan and Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diprivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diprivan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sertraline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on propofol and sertraline hydrochloride (the active ingredients of Diprivan and Sertraline, respectively), and Diprivan and Sertraline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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