Dipyrone and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dipyrone (metamizole) and Acyclovir (acyclovir). Common drug interactions include confusional state among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Dipyrone and Acyclovir. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Dipyrone?

Dipyrone has active ingredients of metamizole. eHealthMe is studying from 1,876 Dipyrone users. Check the latest studies of Dipyrone.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

On Jul, 27, 2026

78 people who take Dipyrone and Acyclovir together, and have interactions are studied.

Dipyrone and Acyclovir drug interactions.

What are the common drug interactions of Dipyrone and Acyclovir, by gender? *:

female:

Confusional state
Fatigue (feeling of tiredness)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Oedema (fluid collection in tissue)
Pleural effusion (water on the lungs)
Weight increased
Dyspnoea exertional (breathlessness or shortness of breath)
Abdominal pain upper
Bilirubin conjugated increased
Bradycardia (abnormally slow heart action)

male:

Neutropenia (an abnormally low number of neutrophils)
Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)
Respiratory syncytial virus infection (viral disease of respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Amaurosis (partial or total blindness without visible change in the eye)
Cardiogenic shock (inadequate circulation of blood)
Coma (state of unconsciousness lasting more than six hours)
Headache (pain in head)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the common drug interactions of Dipyrone and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Vision blurred
Amaurosis (partial or total blindness without visible change in the eye)
Headache (pain in head)
Coma (state of unconsciousness lasting more than six hours)
Cytomegalovirus infection
Diarrhoea
Erythema multiforme (a type of hypersensitivity reaction)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)

10-19:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Central nervous system haemorrhage (bleeding in brain and surrounding)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Headache (pain in head)
Hepatomegaly (abnormal enlargement of the liver)
Hypertension (high blood pressure)
Incoherent (talking in a confused and unclear way)
Oral disorder (mouth disease)
Retinal oedema (swelling of retina)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sopor (sleep)
Unresponsive to stimuli

30-39:

Abdominal pain

40-49:

Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
Febrile neutropenia (fever with reduced white blood cells)
Dyspnoea exertional (breathlessness or shortness of breath)
Infusion related reaction
Acute hepatic failure
Alanine aminotransferase increased
Aspartate aminotransferase increased
Asthenia (weakness)
Back disorder
Blood pressure increased

50-59:

Cardiogenic shock (inadequate circulation of blood)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Gastroenteritis (inflammation of stomach and intestine)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Pyrexia (fever)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

60+:

Pleural effusion (water on the lungs)
Septic shock (shock due to blood infection)
Pain in extremity
Pulmonary congestion (congestion in the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)
Activated partial thromboplastin time prolonged
Arthralgia (joint pain)
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Blood bicarbonate decreased

What are the existing conditions these people have? *

Burkitt Lymphoma (cancer of the lymphatic system): 22 people, 28.21%
Nausea And Vomiting: 15 people, 19.23%
Pain: 15 people, 19.23%
High Blood Pressure: 11 people, 14.10%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 9 people, 11.54%
Depression: 9 people, 11.54%
Nausea (feeling of having an urge to vomit): 8 people, 10.26%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 8 people, 10.26%
Multiple Myeloma (cancer of the plasma cells): 7 people, 8.97%
Fever: 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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