Ditropan and Dantrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Dantrium (dantrolene sodium). Common drug interactions include procedural nausea among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Dantrium. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Dantrium?

Dantrium has active ingredients of dantrolene sodium. eHealthMe is studying from 1,408 Dantrium users. Check the latest studies of Dantrium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

46 people who take Ditropan and Dantrium together, and have interactions are studied.

Ditropan and Dantrium drug interactions.

What are the common drug interactions of Ditropan and Dantrium, by gender? *:

female:

Procedural nausea
Procedural pain
Pruritus (severe itching of the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pulmonary thrombosis (scarring in the lungs)
Rectal bleeding (bleeding from rectum)
Red blood cell count decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenic purpura (a bleeding disorder in which the immune system destroys platelets)

male:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion
Arrhythmia (irregular heartbeat)
C-reactive protein increased
Cellulitis (infection under the skin)
Conduction disorder (serious disorder of the heart not responses proper to impulses)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug dependence
Face oedema (swelling of face)
Fracture

What are the common drug interactions of Ditropan and Dantrium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abortion induced (medically referred abortion)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Drug exposure during pregnancy
Macule (a discoloured spot on the skin)

30-39:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion
Sepsis (a severe blood infection that can lead to organ failure and death)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

40-49:

Tooth disorder (tooth disease)
Tooth injury
Chest pain
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Arthralgia (joint pain)
Depression
Dyspnoea (difficult or laboured respiration)
Ear disorder
Heart rate increased
Hypertension (high blood pressure)

50-59:

Haemoglobin decreased
Pneumonia
Acute hepatic failure
Blood glucose increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cystitis (inflammation of the wall of the bladder)
Fall
Haematocrit decreased
Hepatitis acute
Influenza like illness

60+:

Altered state of consciousness (altered state of mind)
Erythema (redness of the skin)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Hypotension (abnormally low blood pressure)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypertension (high blood pressure)
Influenza like illness
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
Nosocomial infection (infection from hospital)
Pneumonia

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 17.39%
Neuromyelitis Optica (inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis)): 3 people, 6.52%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 6.52%
Depression: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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