Feldene and Bone pain aggravated - a phase IV clinical study of FDA data

Summary:

Bone pain aggravated is reported as a side effect among people who take Feldene (piroxicam), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Lexapro, and have Depression.

The phase IV clinical study analyzes which people have Bone pain aggravated when taking Feldene. It is created by eHealthMe based on reports of 3,850 people who have side effects when taking Feldene from the FDA, and is updated regularly.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.

What is Bone pain aggravated?

Bone pain aggravated is found to be associated with 1,428 drugs and 425 conditions by eHealthMe. Check the latest studies of Bone pain aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

3,850 people reported to have side effects when taking Feldene.
Among them, 47 people (1.22%) have Bone pain aggravated.

Could Feldene cause Bone pain aggravated?

Among these 47 people:

How long have people been on Feldene when they have Bone pain aggravated? *

What is the gender of people who have Bone pain aggravated when taking Feldene? *

female: 47.83 %
male: 52.17 %

What is the age of people who have Bone pain aggravated when taking Feldene? *

What are other drugs people take besides Feldene? *

What are other side effects people have besides Bone pain aggravated? *

Stress And Anxiety: 38 people, 80.85%
Pain: 36 people, 76.60%
Neuropathy Peripheral (surface nerve damage): 34 people, 72.34%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 33 people, 70.21%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 33 people, 70.21%
Anaemia (lack of blood): 30 people, 63.83%
Osteonecrosis Of Jaw (death of bone of jaw): 27 people, 57.45%
Insomnia (sleeplessness): 27 people, 57.45%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 26 people, 55.32%
Depression: 25 people, 53.19%

What are the existing conditions these people have? *

Depression: 24 people, 51.06%
Multiple Myeloma (cancer of the plasma cells): 22 people, 46.81%
Arrhythmias (irregular heartbeat): 22 people, 46.81%
Stable Angina (a constant chest pain): 22 people, 46.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 23.40%
Back Pain: 5 people, 10.64%
Osteoporosis (bones weak and more likely to break): 5 people, 10.64%
High Blood Pressure: 4 people, 8.51%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 6.38%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

Do you take Feldene and have Bone pain aggravated?

- Check whether Bone pain aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Feldene:

Feldene (3,913 reports)

Browse all side effects of Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone pain aggravated:

Bone pain aggravated (1,429 drugs)

Browse all the conditions that are associated with Bone pain aggravated:

Bone pain aggravated (425 conditions)

Related publications that referenced our studies

Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .
Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on piroxicam (the active ingredients of Feldene) and Feldene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.