Ditropan and Neupogen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Neupogen (filgrastim). Common drug interactions include asthenia among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Ditropan and Neupogen. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Ditropan?
Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.
What is Neupogen?
Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.
14 people who take Ditropan and Neupogen together, and have interactions are studied.

What are the common drug interactions of Ditropan and Neupogen, by gender? *:
female:
- Asthenia (weakness)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood bilirubin increased
- Cardiac failure congestive
- Cellulitis (infection under the skin)
- Decreased appetite
- Erythema multiforme (a type of hypersensitivity reaction)
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Gastritis (inflammation of stomach)
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Pain
- Physical disability
- Renal impairment (severely reduced kidney function)
- Tooth fracture
- Tooth loss
- Pericarditis (inflammation of the pericardium)
- Atherosclerosis (disorder of the arteries)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the common drug interactions of Ditropan and Neupogen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood bilirubin increased
- Cellulitis (infection under the skin)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
30-39:
- Pericarditis (inflammation of the pericardium)
- Cystitis haemorrhagic (blood in the urine and painful voiding)
- Haematuria (presence of blood in urine)
- Urethral pain
40-49:
- Dyspnoea (difficult or laboured respiration)
- Respiratory distress (difficulty in breathing)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Cerebral haemorrhage (bleeding within the brain)
- Emotional distress
- Fear of falling
- Nephrolithiasis (calculi in the kidneys)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
60+:
- Asthenia (weakness)
- Atherosclerosis (disorder of the arteries)
- Hospitalisation
- Impaired gastric emptying
- Malaise (a feeling of general discomfort or uneasiness)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia
- Pneumonia viral
- Renal cyst (kidney cyst)
- Respiratory failure (inadequate gas exchange by the respiratory system)
What are the existing conditions these people have? *
- Fever: 2 people, 14.29%
- Rashes (redness): 2 people, 14.29%
- Hiv Infection: 2 people, 14.29%
- Nausea (feeling of having an urge to vomit): 2 people, 14.29%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.14%
- Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 1 person, 7.14%
- Cough: 1 person, 7.14%
- Constipation: 1 person, 7.14%
- Chronic Renal Failure (kidney failure): 1 person, 7.14%
- Cardiac Failure: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Ditropan and Neupogen?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ditropan and Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ditropan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ditropan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neupogen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxybutynin chloride and filgrastim (the active ingredients of Ditropan and Neupogen, respectively), and Ditropan and Neupogen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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